Plasma Electrolytic Oxidation (PEO) Coatings for Biomedical Implants: A Review on Enhancing Antibacterial Efficacy Through Controlled Antibiotic Release
Source abstract
Abstract
The use of biomedical implants has significantly enhanced patient survival rates and overall quality of life. However, bacterial infections caused by bacterial adhesion and the subsequent formation of biofilm on the surface of the implants are challenging clinical issues, leading to implant failure and high social and economic costs. Modification of the surface of the implants with antibacterial coatings is a promising technique to address implant-associated bacterial infection problems. One strategy to fabricate bactericidal antibacterial coatings is to load antibacterial agents, like antibiotics—the most important type of antibacterial drug for killing or inhibiting the growth of bacteria—at therapeutic doses into the coatings and subsequently release them, ideally in a controlled way. Plasma electrolytic oxidation (PEO) is a simple, affordable, and eco-friendly method to produce high-performance, multifunctional coatings with desired antibacterial properties. This review examines the antibacterial activity of antibiotic-loaded PEO coatings, offering valuable insights for the development of novel, high-performance antibacterial coatings that meet clinical requirements.
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Advanced Photocatalysis Techniques · Polymer Surface Interaction Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Materials Engineering, Hamedan University of Technology, Hamedan 65169-13733, Iran
Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran
Department of Materials Science and Engineering, Faculty of Engineering, Ferdowsi University of Mashhad, Mashhad 91775-1111, Iran
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