journal article·2023-01-08Open access

Mathematical Modeling and Analysis of the Steady Electro-Osmotic Flow of Two Immiscible Fluids: A Biomedical Application

Haifa A. Alyousef, Humaira Yasmin, Rasool Shah, Nehad Ali Shah, Lamiaa S. El-Sherif, Samir A. El-Tantawy

Coatings· Volume 13· Issue 1

Abstract

The in vitro fabrication of big osteoarticular implants integrating biomaterials and cells is of tremendous interest because these tissues have a limited ability to regenerate. However, the growth of such cells in vitro is highly problematic, especially later in the culture, when the extracellular matrix has almost filled the initial porous network. Thus, the fluid flow required to properly perfuse the sample cannot be obtained by the hydraulic driving force alone. Fluid pumping is a central concern of a microfluidic system and electro-osmotic pumps (EOPs) are commonly employed for this purpose. Using electro-kinetic equations as a basis, this study analyzed the variations of a two-fluid electro-osmotic flow of viscoelastic fluid flow through a channel. The behavior of the fluid was studied through the Ellis equation. This is how the electro-osmotic pump functions, as demonstrated in the literature that it electrically drags a conducting fluid across a non-conducting fluid through interfacial dragging force along the channel. A steady-state analytical solution for the system in a conducting fluid channel was studied by undertaking an interface planner for fluids exhibiting Newtonian rheological properties. The pumping characteristics were studied in detail by using the Ellis model’s parameters. The fluid rheology was studied, which showed the viability of this technique.
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Research context

OpenAlex topics: Microfluidic and Bio-sensing Technologies · Microfluidic and Capillary Electrophoresis Applications · 3D Printing in Biomedical Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Physics, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

Department of Basic Sciences, Preparatory Year Deanship, King Faisal University, Al-Ahsa 31982, Saudi Arabia

Department of Mathematics, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan

Department of Mechanical Engineering, Sejong University, Seoul 05006, Republic of Korea

Department of Physics, College of Arts and Science in Wadi Al-Dawaser, Prince Sattam Bin Abdulaziz University, Wadi-Dawaser 11991, Saudi Arabia

Department of Physics, Faculty of Science, Port Said University, Port Said 42521, Egypt

Research Center for Physics (RCP), Department of Physics, Faculty of Science and Arts, Al-Mikhwah, Al-Baha University, Al-Baha 1988, Saudi Arabia

Funding

Princess Nourah bint Abdulrahman University · Deanship of Scientific Research · Prince Sattam bin Abdulaziz University

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Show source-provided references
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