Surface Roughness Analysis of Microchannels Featuring Microfluidic Devices Fabricated by Three Different Materials and Methods
Source abstract
Abstract
In recent years, the utilization of microfluidic devices for precise manipulation of small flows has significantly increased. The effective management of microfluidics is closely associated with microchannel fabrication. The fabrication method employed for microfluidic devices directly impacts the roughness of the microchannels, consequently influencing the flows within them. In this study, the surface roughness of microchannels was investigated through three different fabrication processes: PDMS lithography, PLA printing, and UV resin printing. This research compared and analyzed the surface roughness of the microchannels fabricated using these methods. Furthermore, supported by a dynamic fluid simulator, the impact of surface roughness on flow behavior was shown. Results reveal varying degrees of roughness prominence in curved regions. Comparing microfluidic device fabrication techniques is crucial to optimize the process, control roughness, analyze flow rates, and select a proper material to be used in the development of microfluidic devices.
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Research context
OpenAlex topics: Microfluidic and Capillary Electrophoresis Applications · Surface Modification and Superhydrophobicity · Innovative Microfluidic and Catalytic Techniques Innovation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Chemical Engineering Department, University Center for Applied Science and Enginnering (CUCEI), Universidad de Guadalajara, Blvd. Marcelino García Barragán 1421, esq Calzada Olímpica, Guadalajara 44430, Mexico
Electronics Department, University Center for Applied Science and Enginnering (CUCEI), Universidad de Guadalajara, Blvd. Marcelino García Barragán 1421, esq Calzada Olímpica, Guadalajara 44430, Mexico
Department of Chemical and Biological Engineering, Illinois Institute of Technology, 10 West 33rd Street, Chicago, IL 60616, USA
Funding
Conacyt
References (39)
Show source-provided references
1. A scalable active micro-mixer for biomedical applications10.1007/s10404-017-1868-9 ↗
2. Analytical detection techniques for droplet microfluidics—A review10.1016/j.aca.2013.04.064 ↗
3. Thermal and hydrodynamic analysis of microchannel heat sinks: A review10.1016/j.rser.2013.01.022 ↗
4. Production of hydrogel microparticles in microfluidic devices: A review10.1007/s10404-020-02413-8 ↗
5. Formation of PEG-DA polymerized microparticles by different microfluidics devices: A T-junction device and a flow focusing device10.1016/j.matpr.2019.03.168 ↗
6. PDMS microfluidics: A mini review10.1002/app.48958 ↗
7. A review of cooling in microchannels10.1080/01457632.2010.506390 ↗
8. Microfluidic electronics10.1039/c2lc21176a ↗
9. Zhang, Y. (2018). On Study of Application of Micro-reactor in Chemistry and Chemical Field. IOP Conf. Ser. Earth Environ. Sci., 113.10.1088/1755-1315/113/1/012003 ↗
10. Design and fabrication of 3-dimensional helical structures in polydimethylsiloxane for flow control applications10.1007/s00542-013-1738-7 ↗
11. Review on ultrasonic fabrication of polymer micro devices10.1016/j.ultras.2014.08.007 ↗
12. Surface roughness study on microchannels of CO2 laser fabricating PMMA-based microfluidic chip10.1142/S0218625X17500172 ↗
13. Scott, S.M., and Ali, Z. (2021). Fabrication methods for microfluidic devices: An overview. Micromachines, 12.10.3390/mi12030319 ↗
14. Review in manufacturing methods of nanochannels of bio-nanofluidic chips10.1016/j.snb.2017.07.139 ↗
15. Precise glass microstructuring with laser induced backside wet etching using error-compensating scan path10.1016/j.jmatprotec.2021.117046 ↗
16. Gottmann, J., Hermans, M., Repiev, N., and Ortmann, J. (2017). Selective laser-induced etching of 3D precision quartz glass components for microfluidic applications-up-scaling of complexity and speed. Micromachines, 8.10.3390/mi8040110 ↗
17. Niino, H., Kawaguchi, Y., Sato, T., Narazaki, A., and Kurosaki, R. (2008, January 19–24). Surface microstructures of silica glass by laser-induced backside wet etching. Proceedings of the SPIE, San Jose, CA, USA.10.1117/12.762240 ↗
18. Otuka, A.J., Tomazio, N.B., Paula, K.T., and Mendonça, C.R. (2021). Two-photon polymerization: Functionalized microstructures, micro-resonators, and bio-scaffolds. Polymers, 13.10.3390/polym13121994 ↗
19. Microfabrication by two-photon lithography, and characterization, of SiO2/TiO2 based hybrid and ceramic microstructures10.1007/s10971-020-05355-3 ↗
20. Butkutė, A., and Jonušauskas, L. (2021). 3d manufacturing of glass microstructures using femtosecond laser. Micromachines, 12.10.3390/mi12050499 ↗
21. Evolution of microstructures on stainless steel induced by ultra-short pulsed laser ablation10.1007/s42452-020-2447-3 ↗
22. Optical modeling of laser ablation for microstructure fabrication10.2961/jlmn.2013.01.0012 ↗
23. Effect of surface roughness on liquid friction and transition characteristics in micro- and mini-channels10.1016/j.applthermaleng.2014.03.028 ↗
24. A numerical study on the effects of 2d structured sinusoidal elements on fluid flow and heat transfer at microscale10.1016/j.ijheatmasstransfer.2012.10.004 ↗
25. Experimental investigation of surface roughness effects on flow behavior and heat transfer characteristics for circular microchannels10.1016/j.cja.2016.10.006 ↗
26. Investigations on the flow behaviour in microfluidic device due to surface roughness: A computational fluid dynamics simulation10.1007/s00542-019-04304-7 ↗
27. Effect of wall roughness on performance of microchannel applied in microfluidic device10.1007/s00542-018-4124-7 ↗
28. Surface roughness effect on droplet impact characterization: Experimental and theoretical study10.15282/jmes.13.2.2019.23.0420 ↗
29. Hydrogel microparticles for biomedical applications10.1038/s41578-019-0148-6 ↗
30. Microfluidic fabrication of microparticles for biomedical applications10.1039/C7CS00263G ↗
31. The potential applications of microparticles in the diagnosis, treatment, and prognosis of lung cancer10.1186/s12967-022-03599-x ↗
32. Sherstneva, A.A., Demina, T.S., Monteiro, A.P., Akopova, T.A., Grandfils, C., and Ilangala, A.B. (2022). Biodegradable Microparticles for Regenerative Medicine: A State of the Art and Trends to Clinical Application. Polymers, 14.10.3390/polym14071314 ↗
33. Acosta-Cuevas, J.M., Gonzalez-Garcaa, J., Garcia-Ramirez, M., Perez-Luna, V.H., Cisneros-Lopez, E.O., Gonzalez-Nuñez, R., and González-Reynoso, O. (2021). Generation of photopolymerized microparticles based on pegda using microfluidic devices. Part 1. initial gelation time and mechanical properties of the material. Micromachines, 12.10.3390/mi12030293 ↗
34. Dow Corning (2018). Silicone Elastomer Technical Data Sheet, Available online: https://www.dow.com/es-es/document-viewer.html?docPath=/content/dam/dcc/documents/en-us/productdatasheet/11/11-12/11-1251-01-sylgard-182-silicone-elastomer.pdf.
35. Fundamental studies of a novel, biodegradable PEG-b-PLA hydrogel
36. Interfacial tension between oil and water measured with a modified contour method10.1016/j.colsurfa.2013.03.010 ↗
37. Level Set Method10.1016/B978-0-12-815485-4.00019-X ↗
38. COMSOL (2016). COMSOL Multiphysics User’s Guide, CMU Guide.
39. Numerical Study of Shear-Thinning Droplet Breakup Dynamics at Microfluidics T-Junction using Level-Set Method