Antibacterial Activity and Bioactivity of Zn-Doped TiO2 Coating for Implants
Source abstract
Abstract
Lacking osseointegration and peri-implantitis induced by bacterial infiltration are the pivotal issues for the long-term clinical success of implants. In order to improve the bioactivity and antibacterial properties of implant materials, volcano-shaped microporous TiO2 coatings doped with Zinc (Zn) were fabricated via a micro-arc oxidation (MAO) method on pure titanium (Ti). The microstructure, morphology, and chemical composition of the Zn-doped coatings were systematically studied. In cell culture tests, the formed coatings promoted the adhesion and proliferation of bone mesenchymal stem cells (BMSCs), exhibiting good biocompatibility. The antibacterial experiments revealed that Zn-TiO2 coatings possess excellent antibacterial properties against Staphylococcus aureus (S. aureus) and Porphyromonas gingivalis (P. gingivalis).
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Dental Implant Techniques and Outcomes · Dental materials and restorations
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Materials and Chemistry, University of Shanghai for Science & Technology, Shanghai 200093, China
Medical College, Anhui University of Science and Technology, Huainan 232002, China
Department of Prosthodontics, Shanghai Stomatological Hospital, Fudan University, Shanghai 200437, China
Shanghai Key Laboratory of Craniomaxill of Acial Development and Diseases, Fudan University, Shanghai 200437, China
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