Corrosion and Biocompatibility of Pure Zn with a Micro-Arc-Oxidized Layer Coated with Calcium Phosphate
Source abstract
Abstract
Recent studies have indicated a great demand to optimize the biocompatibility properties of pure Zn as an implant material. For this purpose, CaZn2(PO4)2·2H2O (CaZnP) was prepared using hydrothermal treatment (HT) combined with micro-arc oxidation (MAO) on pure Zn substrate to generate biodegradable implants. The polarization test and electrochemical impedance spectroscopy indicated that the MAO1−HT coating could modulate the corrosion behavior of MAO1 by filling the crevice between the coating and the substrate. Immersion test evaluation revealed that the osteogenic properties of MAO1−HT coating were better than that of pure Zn substrate, as evidenced by the molar ratio of Ca and P, which increased after soaking in simulated body fluid (SBF) for up to 10 days. In addition, L-929 cells cultured in the 100%, 50%, and 25% extracts of MAO1−HT coated samples exhibited excellent cytocompatibility. Meanwhile, cell adhesion was promoted on the surface with high roughness generated during MAO and HT processes. In summary, the calcified coatings improved biocompatibility and adjusted the degradation rates of pure Zn, broadening the application of Zn alloys.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Magnesium Alloys: Properties and Applications · Bone Tissue Engineering Materials · Corrosion Behavior and Inhibition
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Materials Science and Engineering, Taiyuan University of Science and Technology, Taiyuan 030024, China
Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China
Ningbo Powerway Alloy Material Co., Ltd., Ningbo 315145, China
Ningbo Medical Center Lihuili Hospital, Ningbo 315040, China
Department of Bioengineering, University of California, Riverside, CA 92521, USA
Funding
the National Key Research and Development Program · Ningbo Science Technology Innovation 2025 Major Project · Natural Science Foundation of Shanxi Province, China
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