journal article·2022-09-25Open access

Human Teeth Disease Detection Using Refractive Index Based Surface Plasmon Resonance Biosensor

Mohammad Khursheed Alam, Vigneswaran Dhasarathan, Ayyanar Natesan, Ramanujam Nambi, Mahmud Uz Zaman, Kiran Kumar Ganji, Rehana Basri, Manay Srinivas Munisekhar, Anil Kumar Nagarajappa, Huda Abutayyem

Coatings· Volume 12· Issue 10

Abstract

The paper proposes a surface plasmon resonance (SPR) biosensor utilizing MXene and a Molybdenum Disulfide (MoS2) material layer, placed on the Ag metal-based conventional biosensor to detect disease in human teeth. The SPR biosensor works on the principle of attenuated total reflection. The transverse matrix method was utilized for the reflectivity calculation. The thickness of the Ag layer, MXene, and MoS2 were taken as 45, 0.993, and 0.375 nm, respectively. Single-layer MoS2 and two layers of MXene were taken, and the highest sensitivity of the sensor for the enamel, dentin, and cementum was obtained at 83.219 deg/RIU, 91.460 deg/RIU, and 104.744 deg/RIU. MoS2 was used to enhance the biocompatibility of the analyte with the sensing layer. The aqueous solution had been considered as sensing medium.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · MXene and MAX Phase Materials · RNA Interference and Gene Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Preventive Dentistry Department, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia

Department of Electronics and Communication Engineering, KPR Institute of Engineering and Technology, Coimbatore 641407, India

Centre for IoT and AI (CITI), KPR Institute of Engineering and Technology, Coimbatore 641407, India

Department of Electronics and Communication Engineering, Thiagarajar College of Engineering, Madurai 625015, India

Department of Physics, K.L.N. College of Engineering, Chennai 630611, India

Oral and Maxillofacial Surgery and Diagnostic Sciences Department, College of Dentistry, Prince Sattam Bin Abdulaziz University, Al-Kharj 16245, Saudi Arabia

Department of Internal Medicine, College of Medicine, Jouf University, Sakaka 72345, Saudi Arabia

Oral Medicine & Radiology Division, Department of Oral & Maxillofacial Surgery & Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia

Department of Clinical Sciences, Center of Medical and Bio-Allied Health Sciences Research, College of Dentistry, Ajman University, Ajman 346, United Arab Emirates

Funding

Deanship of Scientific Research at Jouf University

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