journal article·2020-01-28Open access

Characterization of Nano-Scale Hydroxyapatite Coating Synthesized from Eggshells Through Hydrothermal Reaction on Commercially Pure Titanium

Hsing-Ning Yu, Hsueh-Chuan Hsu, Shih-Ching Wu, Cheng-Wei Hsu, Shih-Kuang Hsu, Wen-Fu Ho

Coatings· Volume 10· Issue 2

Abstract

Commercially pure titanium (c.p. Ti) is often used in biomedical implants, but its surface cannot usually combine with the living bone. A coating of hydroxyapatite (HA) on the surface of titanium implants provides excellent mechanical properties and has good biological activity and biocompatibility. For optimal osteocompatibility, the structure, size, and composition of HA crystals should be closer to those of biological apatite. Our results show that the surface of c.p. Ti was entirely covered by rod-like HA nanoparticles after alkali treatment and subsequent hydrothermal treatment at 150 °C for 48 h. Nano-sized apatite aggregates began to nucleate on HA-coated c.p. Ti surfaces after immersion in simulated body fluid (SBF) for 6 h, while no obvious precipitation was found on the uncoated sample. Higher apatite-forming ability (bioactivity) could be acquired by the samples after HA coating. The HA coating featured bone-like nanostructure, high crystallinity, and carbonate substitution. It can be expected that HA coatings synthesized from eggshells on c.p. Ti through a hydrothermal reaction could be used in dental implant applications in the future.
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Research context

OpenAlex topics: Bone Tissue Engineering Materials · Titanium Alloys Microstructure and Properties · Dental Implant Techniques and Outcomes

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Surgery, Division of Orthopaedics, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung 81342, Taiwan

Department of Dental Technology and Materials Science, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan

Department of Materials Science and Engineering, Da-Yeh University, Changhua 51591, Taiwan

Department of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan

Funding

Zuoying Branch of Kaohsiung Armed Forces General Hospital and National University of Kaohsiung

References (41)

Show source-provided references
1. Yeo, I.-S.L. (2020). Modifications of dental implant surfaces at the microand nano-level for enhanced osseointegration. Materials, 13.10.3390/ma13010089 ↗
2. Corrosion resistance with self-healing behavior and biocompatibility of Ce incorporated niobium oxide coated 316L SS for orthopedic applications10.1016/j.surfcoat.2019.07.042 ↗
3. Effect of transition layer on the performance of hydroxyapatite/titanium nitride coating developed on Ti–6Al–4V alloy by magnetron sputtering10.1016/j.ceramint.2018.11.183 ↗
4. Electrodeposition of hydroxyapatite onto nanotubular TiO2 for implant applications10.1016/j.surfcoat.2006.09.008 ↗
5. Odhiambo, J.G., Li, W.G., Zhao, Y.T., and Li, C.L. (2019). Porosity and its significance in plasma-sprayed coatings. Coatings, 9.10.3390/coatings9070460 ↗
6. Osteointegration of biomimetic apatite coating applied onto dense and porous metal implants in femurs of goats
7. Aydın, İ., Bahçepınar, A.İ., Kırman, M., and Çipiloğlu, M.A. (2019). HA coating on Ti6Al7Nb alloy using an electrophoretic deposition method and surface properties examination of the resulting coatings. Coatings, 9.10.3390/coatings9060402 ↗
8. In-vitro comparison of hydroxyapatite coatings obtained by cold spray and conventional thermal spray technologies10.1016/j.msec.2019.110306 ↗
9. Sputter deposition of calcium phosphate/titanium dioxide hybrid thin films10.1016/j.msec.2006.12.004 ↗
10. Investigation of functionally graded HA-TiO2 coating on Ti–6Al–4V substrate fabricated by sol-gel method10.1016/j.ceramint.2019.05.317 ↗
11. The effect of temperature and initial pH on biomimetic apatite coating10.1002/jbm.b.31096 ↗
12. A hydrothermal synthesis of eggshell and fruit waste extract to produce nanosized hydroxyapatite10.1016/j.ceramint.2013.03.094 ↗
13. Hydroxyapatite synthesized from oyster shell powders by ball milling and heat treatment10.1016/j.matchar.2011.09.009 ↗
14. Electrochemical performances of activated carbon prepared using eggshell waste10.1007/s42452-019-1921-2 ↗
15. Biological hydroxyapatite obtained from fish bones10.1016/j.msec.2011.11.021 ↗
16. Micro-arc oxidation of bioceramic coatings containing eggshell-derived hydroxyapatite on titanium substrate10.1016/j.ceramint.2019.06.052 ↗
17. Sintering behavior and characteristic of bio-based hydroxyapatite coating deposited on titanium
18. Bone-like nano-hydroxyapatite coating on low-modulus Ti–5Nb–5Mo alloy using hydrothermal and post-heat treatments10.1016/j.tsf.2019.137463 ↗
19. The deposition of γ-Al2O3 layers on ceramic and metallic supports for the preparation of structured catalysts10.1016/j.surfcoat.2004.03.007 ↗
20. How useful is SBF in predicting in vivo bone bioactivity?10.1016/j.biomaterials.2006.01.017 ↗
21. One-step modification of nano-hydroxyapatite coating on titanium surface by hydrothermal method10.1016/j.surfcoat.2010.08.088 ↗
22. Effects of hydrothermal treatment with CaCl2 solution on surface property and cell response of titanium implants10.1007/s10856-005-4753-0 ↗
23. 3D microenvironment as essential element for osteoinduction by biomaterials10.1016/j.biomaterials.2004.09.056 ↗
24. Nanomedicine for implants: A review of studies and necessary experimental tools10.1016/j.biomaterials.2006.08.049 ↗
25. Surface modification of commercially pure Ti treated with aqueous NaOH treatment and ethyl alcohol aging10.5405/jmbe.1021 ↗
26. Preparation of bioactive Ti–15Zr–4Nb–4Ta alloy from HCl and heat treatments after an NaOH treatment10.1002/jbm.a.33036 ↗
27. Improvement of the bioactivity of H2O2/TaCl5-treated titanium after subsequent heat treatment10.1002/1097-4636(200010)52:1<171::AID-JBM22>3.0.CO;2-O ↗
28. Time-dependent growth of biomimetic apatite on anodic TiO2 nanotubes10.1016/j.electacta.2008.01.027 ↗
29. The role of hydrated silica, titania, and alumina in inducing apatite on implants10.1002/jbm.820280103 ↗
30. FT-IR characterization of the surface acidity of different titanium dioxide anatase preparations10.1016/S0166-9834(00)84358-4 ↗
31. Lewis acid and base sites at the surface of microcrystalline TiO2 anatase: Relationships between surface morphology and chemical behaviour10.1016/S0926-860X(00)00641-4 ↗
32. Spectroscopic analysis of titanium surface functional groups under various surface modification and their behaviours in vitro and in vivo10.1002/jbm.a.31471 ↗
33. The effects of hydroxyl groups on Ca adsorption on rutile surface: A first-principles study10.1007/s10856-009-3828-8 ↗
34. Nano-Ag-loaded hydroxyapatite coatings on titanium surfaces by electrochemical deposition10.1098/rsif.2010.0366 ↗
35. Surface characteristics and dissolution behavior of plasma-sprayed hydroxyapatite coating10.1002/jbm.10315 ↗
36. Effect of crystallinity of calcium phosphate nanoparticles on adhesion, proliferation, and differentiation of bone marrow mesenchymal stem cells10.1039/b710936a ↗
37. Ultrasonic cleaning of silica-coated zirconia influences bond strength between zirconia and resin luting material10.4012/dmj.27.842 ↗
38. The effect of ultrasonic irradiation on the crystallinity of nano-hydroxyapatite produced via the wet chemical method10.1016/j.msec.2013.02.027 ↗
39. Calcium phosphate bioceramics synthesized from eggshell powders through a solid state reaction10.1016/j.ceramint.2013.01.076 ↗
40. Ionic substitutions in calcium phosphates synthesized at low temperature10.1016/j.actbio.2009.12.041 ↗
41. Magnesium deficiency and osteoporosis: Animal and human observations10.1016/j.jnutbio.2004.08.001 ↗