Kinetically Deposited Copper Antimicrobial Surfaces
Source abstract
Abstract
Bacterial and viral contamination of contact surfaces increases the risk of infection. A great deal of work has been done on the capabilities of copper and its alloys to protect against a variety of microorganisms endangering public health, particularly in healthcare and food processing applications. This work has conclusively shown the effectiveness of copper for touch surface disinfection; however, the optimum microstructural characteristics of the copper surface have not been established. The sterilization effectiveness of three kinetically sprayed copper surfaces and two copper feedstocks were examined. The surfaces were inoculated with methicillin-resistant Staphylococcus aureus (MRSA) and influenza A virus. After a two-hour exposure to the surfaces, the surviving microorganisms were assayed, and the results contrasted. These tests showed substantial antimicrobial differences between the coatings generated by the spray techniques and those obtained by different feedstock powders. The significance of the copper spray application was demonstrated, and the application-dependent mechanism for antimicrobial effectiveness was explained.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Antimicrobial agents and applications · Contact Dermatitis and Allergies · Infection Control in Healthcare
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Army Research Laboratory, Aberdeen Proving Ground, MD 21005-5201, USA
Worcester Polytechnic Institute, Worcester, MA 01609, USA
Survice Engineering, Aberdeen, MD 21017, USA
References (34)
Show source-provided references
1. Antimicrobial surfaces and their potential in reducing the role of the inanimate environment in the incidence of hospital-acquired infections10.1039/b818698g ↗
2. Comparison of results of ATP bioluminescence and traditional hygiene swabbing methods for the determination of surface cleanliness at a hospital kitchen10.1016/j.ijheh.2005.09.007 ↗
3. Bacterial contamination of hospital physicians’ stethoscopes10.1086/501686 ↗
4. Environmental-study of a methicillin-resistant Staphylococcus aureus epidemic in a burn unit10.1128/jcm.18.3.683-688.1983 ↗
5. Microbiological evaluation of hospital cleaning methods10.1080/09603120701372433 ↗
6. Significance of fomites in the spread of respiratory and enteric viral disease10.1128/AEM.02051-06 ↗
7. Transmission of viral respiratory infections in the home10.1097/00006454-200010001-00002 ↗
8. Inactivation of influenza A viruses in the environment and modes of transmission: A critical review10.1016/j.jinf.2008.08.013 ↗
9. Michels, H., Wilks, S., Noyce, J., and Keevil, C. (2005, January 25–28). Copper Alloys for Human Infectious Disease Control. Proceedings of the Materials Science and Technology Conference, Pittsburgh, PA, USA.
10. Superhydrophilicity and antibacterial property of a Cu-dotted oxide coating surface10.1186/1476-0711-9-25 ↗
11. Metallic copper as an antimicrobial surface10.1128/AEM.02766-10 ↗
12. Antibacterial nanostructured composite films for biomedical applications: Microstructural characteristics, biocompatibility, and antibacterial mechanisms10.1080/08927014.2013.769967 ↗
13. CDC (2019, April 15). Infection Control Measures for Preventing and Controlling Influenza Transmission in Long-Term Care Facilities, Available online: https://phpa.health.maryland.gov/OIDEOR/IMMUN/Shared%20Documents/LTCF_FluPrevention_Dec-2005.pdf.
14. Influenza control in the 21st century: Optimizing protection of older adults10.1016/j.vaccine.2009.06.032 ↗
15. CDC (2013). Influenza Activity—United States, 2012–2013 Season and Composition of the 2013–14 Influenza Vaccine. Morb. Mortal. Wkly. Rep., 62, 473–479.
16. Copper Development Association (2019, April 15). Properties of Wrought and Cast Copper Alloys. Available online: http://www.copper.org/resources/properties/db/basic-search.php.
17. Copper Development Association (2019, April 15). The Copper Advantage: A Guide to Working with Copper and Copper Alloys. Available online: https://www.copper.org/publications/pub_list/pdf/a1360.pdf.
18. ALcontrol In-House Methodology (2019, April 15). Test Method for Efficacy of Copper Alloy Surfaces as a Sanitizer. Available online: https://www.antimicrobialcopper.org/sites/default/files/upload/media-library/files/pdfs/uk/miscellaneous/bp51.3-copper-alloy-surfaces-as-a-sanitizer.pdf.
19. Champagne, V., and Helfritch, D. (2013). A demonstration of the antimicrobial effectiveness of various copper surfaces. J. Biol. Eng., 7.10.1186/1754-1611-7-8 ↗
20. Sundberg, K., Champagne, V., McNally, B., Helfritch, D., and Sisson, R. (2015). Effectiveness of nanomaterial copper cold spray surfaces on inactivation of influenza A virus. J. Biotechnol. Biomater., 5.
21. Inactivation of influenza A virus on copper versus stainless steel surfaces10.1128/AEM.01139-06 ↗
22. Bacterial killing by dry metallic copper surfaces10.1128/AEM.01599-10 ↗
23. Inactivation and morphological changes of avian influenza virus by copper ions10.1007/s00705-008-0154-2 ↗
24. Virus inactivation by copper or iron ions alone and in the presence of peroxide10.1128/aem.59.12.4374-4376.1993 ↗
25. Mehrer, H. (2007). Diffusion in Solids, Springer Series in Solid-State Sciences, Springer.10.1007/978-3-540-71488-0 ↗
26. Microstructure refinement of cold-sprayed copper investigated by electron channeling contrast imaging10.1017/S1431927614001664 ↗
27. Microstructural evolution of 6061 aluminum gas-atomized powder and high-pressure cold-sprayed deposition10.1007/s11666-013-0049-y ↗
28. Microstructural bonding features of cold sprayed face centered cubic metals10.1063/1.1789278 ↗
29. Microstructural refinement within a cold-sprayed copper10.1007/s11661-009-9882-5 ↗
30. Dislocation structure and crystallite size in severely deformed copper by X-ray peak profile analysis10.1016/j.msea.2005.03.042 ↗
31. Thermal stability of microstructure and hardness of cold-sprayed cBN/NiCrAI nanocomposite coating10.1007/s11666-011-9719-9 ↗
32. (2019, April 15). Center for Disease Control Prevention, Electron Micrograph of Methicillin-Resistant Staphylococcus aureus (MRSA). Available online: http://faculty.ccbcmd.edu/courses/bio141/lecguide/unit1/shape/EM_MRSA_staph.html.
33. The relationship between substratum surface roughness and microbiological and organic soiling: A review10.1080/08927010109378465 ↗
34. Role of copper oxides in contact killing of bacteria10.1021/la404091z ↗