Enhanced Electrochemical Conductivity of Surface-Coated Gold Nanoparticles/Copper Nanowires onto Screen-Printed Gold Electrode
Source abstract
Abstract
Electrochemical application has been widely used in the study of biosensors. Small biomolecules need a sensitive sensor, as the transducer that can relay the signal produced by biomolecule interactions. Therefore, we are improvising a sensor electrode to enhance electrochemical conductivity for the detection of small DNA molecule interaction. This work describes the enhanced electrochemical conductivity studies of copper nanowires/gold nanoparticles (CuNWs/AuNPs), using the screen-printed gold electrode (SPGE). The AuNPs were synthesized using the Turkevich method as well as characterized by the high-resolution transmission electron microscopy (HRTEM) and ultraviolet-visible (UV-Vis) analysis for the particle size and absorption nature, respectively. Further, the surface morphology and elemental analysis of a series of combinations of different ratios of CuNWs-AuNPs-modified SPGE were analyzed by field emission scanning electron microscopy (FESEM) combined with an energy dispersive X-ray (EDX). The results indicate that the nanocomposites of CuNWs-AuNPs have been randomly distributed and compacted on the surface of SPGE, with AuNPs filling the pores of CuNWs, thereby enhancing its electrochemical conductivity. The cyclic voltammetry (CV) method was used for the evaluation of SPGE performance, while the characterization of the electrochemical conductivity of the electrode modified with various concentrations of AuNPs, CuNWs, and different volumes of dithiopropionic acid (DTPA) has been conducted. Of the various parameters tested, the SPGE modified with a mixture of 5 mg/mL CuNWs and 0.25 mM AuNPs exhibited an efficient electrochemical conductivity of 20.3 µA. The effective surface area for the CuNWs-AuNPs-modified SPGE was enhanced by 2.3-fold compared with the unmodified SPGE, thereby conforming the presence of a large active biomolecule interaction area and enhanced electrochemical activity on the electrode surface, thus make it promising for biosensor application.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Electrochemical Analysis and Applications · Electrochemical sensors and biosensors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Nanoscience and Nanotechnology, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia
Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia
Halal Product Research Institute, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia
Department of Chemistry, Southern University and A&M College, Baton Rouge, LA 70813, USA
Funding
Universiti Putra Malaysia · Researchers Supporting Project
References (43)
Show source-provided references
1. Development and characterisation of disposable gold electrodes, and their use for lead (II) analysis10.1007/s00216-006-0904-5 ↗
2. Determination of arsenic (III) using platinum nanoparticle-modified screen-printed carbon-based electrodes
3. Bismuth-coated screen-printed electrodes for stripping voltammetric measurements of trace lead
4. Vertically aligned diamond nanowires: Fabrication, characterization, and application for DNA sensing10.1002/pssa.200982222 ↗
5. Nanowires array modified electrode for enhanced electrochemical detection of nucleic acid10.1016/j.bios.2012.07.034 ↗
6. Functionalized GaN nanowire-based electrode for direct label-free voltammetric detection of DNA hybridization10.1039/b816556d ↗
7. A novel electrochemical DNA biosensor based on graphene and polyaniline nanowires10.1016/j.electacta.2010.12.034 ↗
8. Construction of highly ordered polyaniline nanowires and their applications in DNA sensing10.1016/j.bios.2013.09.023 ↗
9. Electrodeposition of CoPtP/Au multisegment nanowires: Synthesis and DNA functionalization10.1016/S1452-3981(23)17952-1 ↗
10. A sensitive DNA biosensor fabricated from gold nanoparticles, carbon nanotubes, and zinc oxide nanowires on a glassy carbon electrode10.1016/j.electacta.2010.02.078 ↗
11. Coffer, J. (2014). Overview of semiconducting silicon nanowires for biomedical applications. Semiconducting Silicon Nanowires for Biomedical Applications, Elsevier.10.1533/9780857097712.1.3 ↗
12. Advancements in copper nanowires: Synthesis, purification, assemblies, surface modification, and applications10.1002/smll.201800047 ↗
13. Palladium-copper nanowires-based biosensor for the ultrasensitive detection of organophosphate pesticides10.1016/j.aca.2017.06.004 ↗
14. High performance non-enzymatic glucose biosensor based on copper nanowires–carbon nanotubes hybrid for intracellular glucose study10.1016/j.snb.2013.03.065 ↗
15. Construction of Poly (methylene blue)/Copper Nanowires Modified Electrode for High-Performance Luteolin Sensing10.1149/1945-7111/abc5d9 ↗
16. The vital function of Fe3O4@ Au nanocomposites for hydrolase biosensor design and its application in detection of methyl parathion10.1039/c2nr33107a ↗
17. Bio-inspired synthesis of metal nanomaterials and applications10.1039/C5CS00133A ↗
18. Caffeine electrochemical sensor using imprinted film as recognition element based on polypyrrole, sol-gel, and gold nanoparticles hybrid nanocomposite modified pencil graphite electrode10.1016/j.bios.2014.03.028 ↗
19. Electrochemical sensor and biosensor platforms based on advanced nanomaterials for biological and biomedical applications10.1016/j.bios.2017.12.031 ↗
20. Comparison of four functionalization methods of gold nanoparticles for enhancing the enzyme-linked immunosorbent assay (ELISA)10.3762/bjnano.8.27 ↗
21. Covalent immobilization of gold nanoparticles on a plastic substrate and subsequent immobilization of biomolecules10.1039/D1RA03902D ↗
22. A novel disposable biosensor based on SiNWs/AuNPs modified-screen printed electrode for dengue virus DNA oligomer detection10.1109/JSEN.2015.2417911 ↗
23. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan–platinum nanoparticles/graphene–gold nanoparticles double nanocomposites modified electrode for detection of erythromycin10.1016/j.bios.2012.05.017 ↗
24. The utilization of SiNWs/AuNPs-modified indium tin oxide (ITO) in fabrication of electrochemical DNA sensor10.1016/j.msec.2014.09.010 ↗
25. Highly sensitive electrochemical biosensor based on polyaniline and gold nanoparticles for DNA detection10.1109/JSEN.2017.2787024 ↗
26. A novel electrochemical DNA biosensor based on a gold nanoparticles-reduced graphene oxide-polypyrrole nanocomposite to detect human T-lymphotropic virus-110.1109/JSEN.2020.2993274 ↗
27. A novel hydrazine electrochemical sensor based on gold nanoparticles decorated redox-active 2-amino-4H-chromene-3-carbonitrile10.1109/JSEN.2017.2754281 ↗
28. A novel nanocomposite electrochemical sensor based on green synthesis of reduced graphene oxide/gold nanoparticles modified screen printed electrode for determination of tryptophan using response surface methodology approach10.1016/j.microc.2020.104634 ↗
29. Smartphone-based differential pulse amperometry system for real-time monitoring of levodopa with carbon nanotubes and gold nanoparticles modified screen-printing electrodes10.1016/j.bios.2018.09.082 ↗
30. Electrochemically controlling the size of gold nanoparticles10.1149/1.2358103 ↗
31. Gold nanoparticles embedded on the surface of polyvinyl alcohol layer
32. Two-dimensional arrays of self-assembled gold and sulfur-containing fullerene nanoparticles10.1021/la011667h ↗
33. Gold electrodes modified with self-assembled layers made of sulphur compounds and gold nanoparticles used for selective electrocatalytic oxidation of catecholamine in the presence of interfering ascorbic and uric acids
34. Gold nanoparticle: Synthesis and characterization10.14202/vetworld.2014.72-77 ↗
35. Electrolyte additive induced fast-charge/slow-discharge process: Potassium ferricyanide and potassium persulfate for CoO-based supercapacitors10.1016/j.jcis.2020.05.059 ↗
36. Effect of carbon particle size on electrochemical performance of EDLC10.1149/1.2918304 ↗
37. Gold electrodes modified with gold nanoparticles and thio compounds for electrochemical sensing of dopamine alone and in presence of potential interferents. A comparative study10.1007/s00604-011-0614-3 ↗
38. Nanostructured nickel oxide and its electrochemical behaviour—A brief review10.1016/j.nanoso.2017.07.003 ↗
39. Enzyme-functionalized gold nanowires for the fabrication of biosensors10.1016/j.bioelechem.2007.05.003 ↗
40. Surface modifications to boost sensitivities of electrochemical biosensors using gold nanoparticles/silicon nanowires and response surface methodology approach10.1007/s10853-015-9438-6 ↗
41. Amplified electrochemical DNA sensor based on polyaniline film and gold nanoparticles10.1002/elan.201200434 ↗
42. Electrochemical biosensing utilizing synergic action of carbon nanotubes and platinum nanowires prepared by template synthesis10.1016/j.bios.2006.08.003 ↗
43. Simple and efficient gold nanoparticles deposition on carbon nanotubes with controllable particle sizes10.1016/j.mseb.2008.12.038 ↗