journal article·2022-10-17Open access

Nanoantioxidants: The Fourth Generation of Antioxidants—Recent Research Roadmap and Future Perspectives

Syed Tawab Shah, Zaira Zaman Chowdhury, Khanom Simarani, Wan Jefrey Basirun, Irfan Anjum Badruddin, Mohamed Hussien, Hussein Alrobei, Sarfaraz Kamangar

Coatings· Volume 12· Issue 10

Abstract

Antioxidants work by interacting with free radicals and converting them into harmless chemicals, interfering with the progression of potentially hazardous chain reactions. Antioxidants are useful in treating illnesses induced by free radicals because they help minimize oxidative stress. Antioxidants, whether natural or synthetic, have a limited effect on cellular health and function because of their low absorption, inability to traverse cellular membrane, and disintegration during delivery. The benefits of antioxidants, both natural and synthetic, are comparable. The use of antioxidants that are covalently attached to nanoparticles, or encased in particles with a hollow center, or feature the nanomaterial encapsulation of various origins has been employed to solve these challenges to provide improved stability, slow and slow sustained release, biocompatibility, and targeted administration. This review examines the importance of metal-based antioxidants and methods for enhancing antioxidant activities based on recent studies.
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Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoparticles: synthesis and applications · Carbon and Quantum Dots Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Nanotechnology & Catalysis Research Centre (NANOCAT), Institute of Postgraduate Studies Building, University of Malaya, Block A, Level 3, Kuala Lumpur 50603, Malaysia

Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia

Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia

Mechanical Engineering Department, College of Engineering, King Khalid University, Abha 61413, Saudi Arabia

Department of Chemistry, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia

Agricultural Research Center, Central Agricultural Pesticide Laboratory, Pesticide Formulation Department, Dokki, Giza 12618, Egypt

Department of Mechanical Engineering, College of Engineering, Prince Sattam Bin Abdullaziz University, Al-Kharj 11942, Saudi Arabia

Funding

Deanship of Scientific Research at King Khalid University · University of Malaya

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