Research Progress on Surface Modification of Titanium Implants
Source abstract
Abstract
Implants made of titanium and its alloys are currently widely used in the human body. A series of surface modification methods developed nowadays enable titanium alloy implants to serve effectively in the human body for a long time. This paper reviews three different types of surface modification technologies for biomedical titanium alloys: physical, chemical, and biological, with particular attention to the assistance of these three technologies on the biological properties of titanium alloys. The physical method can change the surface morphology of titanium implants and prepare specific coatings for the implants, such as oxide films, bioactive molecules, drugs, etc. Chemical and biological surface modification technologies can minimize bacterial adhesion on the implant surface, improve the integration of soft tissue around the implant, prevent the occurrence of peri-implantitis, and accelerate the process of damage repair. An ideal titanium implant surface should balance the optimal surface morphology, chemical properties, and bionic characteristics to accelerate bone integration, enhance stability, and reduce peri-implant inflammation. Future research should focus on combining technologies, exploring interactions at the cellular and molecular levels, and conducting extensive in vitro and in vivo studies to verify the effectiveness and safety of modified surfaces. The progress in these fields will help overcome the existing limitations, improve the performance of implants, and obtain better clinical results.
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Dental Implant Techniques and Outcomes · Orthopaedic implants and arthroplasty
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Stomatology, Xuzhou Medical University, No.209 Tongshan Road, Xuzhou 221004, China
Institute of Translational Medicine, Shanghai Jiao Tong University, No.800 Dongchuan Road, Minhang District, Shanghai 200240, China
Nantong Haimen People’s Hospital, No.1201 Beijing Road, Haimen Street, Haimen District, Nantong 226100, China
Funding
Initializing Fund of Xuzhou Medical University · Jiangsu Provincial Health Commission
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