Plasma-Sprayed Hydroxyapatite Coatings and Their Biological Properties
Source abstract
Abstract
Air plasma spraying (APS) is a common method of producing hydroxyapatite (HA) coatings for alloprosthetic implants. Modification of HA spraying potentially may diminish the risk of inflammation and local infection during bone implantation. Titanium implants were HA coated with different deposition process parameters. HA powder was deposited using APS with axial powder injection at three different distances (100, 120, and 140 mm). The surface morphology of each implant was examined and the direct contact cytotoxicity of each HA coating was evaluated according to norm ISO 10993 5:2009. The response of monocytes to HA was assessed via the activation of transcription nuclear factor. All coatings had a lamellar structure. HA sprayed at a distance of 120 mm showed the highest roughness and little phase change. The analysis of the results of the conducted research showed that plasma-spraying distance during the HA coating process had a negligible impact on biocompatibility. The results obtained for a distance of 120 mm showed a slight increase in the biological properties tested. Moreover, HA coatings sprayed at different distances were not cytotoxic and did not stimulate the NF-kB. Bare titanium was less susceptible to colonization by Staphylococcus aureus than HA-coated surfaces. HA constitutes a potentially good, low-cost, non-cytotoxic material for joint prostheses.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Orthopaedic implants and arthroplasty · Titanium Alloys Microstructure and Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Faculty of Mechatronics and Mechanical Engineering, Kielce University of Technology, 25-314 Kielce, Poland
Department of Immunology and Infectious Biology, Faculty of Biology and Environmental Protection, University of Łódź, 90-237 Łódź, Poland
Faculty of Electrical Engineering, Automatic Control and Computer Science, Kielce University of Technology, 25-541 Kielce, Poland
Institute of Metallurgy and Materials Science, Polish Academy of Sciences, 30-059 Kraków, Poland
Department of Microbiology, Institute of Biology, Jan Kochanowski University, 25-406 Kielce, Poland
Funding
Jan Kochanowski University
References (41)
Show source-provided references
1. Review on titanium and titanium based alloys as biomaterials for orthopaedic applications10.1016/j.msec.2019.04.064 ↗
2. Surface Modification of Titanium and Titanium Alloys: Technologies, Developments, and Future Interests10.1002/adem.201901258 ↗
3. Bone bonding bioactivity of Ti metal and Ti–Zr–Nb–Ta alloys with Ca ions incorporated on their surfaces by simple chemical and heat treatments10.1016/j.actbio.2010.09.026 ↗
4. Suspension plasma sprayed bioactive glass coatings: Effects of processing on microstructure, mechanical properties and in-vitro behaviour10.1016/j.surfcoat.2012.10.076 ↗
5. Surface modification of titanium, titanium alloys, and related materials for biomedical applications10.1016/j.mser.2004.11.001 ↗
6. Biomedical Applications of Titanium and its Alloys10.1007/s11837-008-0031-1 ↗
7. Titanium Alloys for Dental Implants: A Review10.3390/prosthesis2020011 ↗
8. Titanium alloys for biomedical applications10.1016/j.msec.2005.08.032 ↗
9. Crystalline hydroxyapatite coatings synthesized under hydrothermal conditions on modified titanium substrates10.1016/j.msec.2015.02.029 ↗
10. Majkowska-Marzec, B., Rogala-Wielgus, D., Bartmański, M., Bartosewicz, B., and Zieliński, A. (2019). Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy. Coatings, 9.10.3390/coatings9100643 ↗
11. Presence and expression of collagen adhesin gene (cna) and slime production in Staphylococcus aureus strains from orthopaedic prosthesis infections10.1016/S0142-9612(99)00099-X ↗
12. Decreased Staphylococcus aureus and increased osteoblast density on nanostructured electrophoretic-deposited hydroxyapatite on titanium without the use of pharmaceuticals
13. Baltatu, M.S., Vizureanu, P., Sandu, A.V., Munteanu, C., and Istrate, B. (2020). Microstructural Analysis and Tribological Behavior of Ti-Based Alloys with a Ceramic Layer Using the Thermal Spray Method. Coatings, 10.10.3390/coatings10121216 ↗
14. Effect of hydrothermal treatment temperature on the hydroxyapatite coatings deposited by electrochemical method10.1016/j.surfcoat.2020.126656 ↗
15. Substituted hydroxyapatite coatings of bone implants10.1039/C9TB02710F ↗
16. Baltatu, M.S., Sandu, A.V., Nabialek, M., Vizureanu, P., and Ciobanu, G. (2021). Biomimetic Deposition of Hydroxyapatite Layer on Titanium Alloys. Micromachines, 12.10.3390/mi12121447 ↗
17. A review on hydroxyapatite coatings for the biomedical applications: Experimental and theoretical perspectives10.1039/D0TB02407D ↗
18. Nazirah, R., Zuhailawati, H., Hazwani, M.R.S.N., Abdullah, T.K., Azzura, I., and Dhindaw, B.K. (2021). The Influence of Hydroxyapatite and Alumina Particles on the Mechanical Properties and Corrosion Behavior of Mg-Zn Hybrid Composites for Implants. Materials, 14.10.3390/ma14216246 ↗
19. Deposition of hydroxyapatite coatings by axial plasma spraying: Influence of feedstock characteristics on coating microstructure, phase content and mechanical properties10.1016/j.jeurceramsoc.2021.02.050 ↗
20. Suspension Plasma-Sprayed Fluoridated Hydroxyapatite/Calcium Silicate Composite Coatings for Biomedical Applications10.1007/s11666-019-00872-2 ↗
21. Solubility, Mechanical and Biological Properties of Fluoridated Hydroxyapatite/Calcium Silicate Gradient Coatings for Orthopedic and Dental Applications10.1007/s11666-020-00981-3 ↗
22. Gil, J., Manero, J.M., Ruperez, E., Velasco-Ortega, E., Jiménez-Guerra, A., Ortiz-García, I., and Monsalve-Guil, L. (2021). Mineralization of titanium surfaces: Biomimetic implants. Materials, 14.10.3390/ma14112879 ↗
23. Interfacial Strength of Plasma-sprayed Hydroxyapatite Coatings10.1007/s11666-020-01041-6 ↗
24. Bovine-derived hydroxyapatite coatings deposited by high-velocity oxygen-fuel and atmospheric plasma spray processes: A comparative study10.1016/j.surfcoat.2019.125193 ↗
25. Corrosion behaviour of plasma sprayed graphene nanoplatelets reinforced hydroxyapatite composite coatings in simulated body fluid10.1016/j.ceramint.2020.02.139 ↗
26. Microstructures and cell reaction of porous hydroxyapatite coatings on titanium discs using a novel vapour-induced pore-forming atmospheric plasma spraying10.1016/j.surfcoat.2020.125837 ↗
27. Preparing hollow spherical hydroxyapatite powder with a thin shell structure by the plasma process with a heat preservation zone10.1016/j.ceramint.2019.06.149 ↗
28. Structure of the hydroxyapatite plasma-sprayed coatings deposited on pre-heated titanium substrates10.1016/j.ceramint.2017.04.057 ↗
29. Fatigue behavior of plasma sprayed structural-grade hydroxyapatite coating under simulated body fluids10.1016/j.surfcoat.2019.04.028 ↗
30. Effect of post-heat treatment on the microstructure of micro-plasma sprayed hydroxyapatite coatings10.1016/j.surfcoat.2019.03.056 ↗
31. Amorphous phase formation in plasma-sprayed hydroxyapatite coatings10.1002/(SICI)1097-4636(19980305)39:3<407::AID-JBM9>3.0.CO;2-N ↗
32. Optical study of plasma sprayed hydroxyapatite coatings deposited at different spray distance
33. Engineering a new class of thermal spray nano-based microstructures from agglomerated nanostructured particles, suspensions and solutions: An invited review10.1088/0022-3727/44/9/093001 ↗
34. Synthesis of nano sized hydroxyapatite powder using sol-gel technique and its conversion to dense and porous bodies
35. Investigation on the structural and microstructural properties of copper-doped hydroxyapatite coatings deposited using solution precursor plasma spraying10.1016/j.jeurceramsoc.2019.06.034 ↗
36. Nanocarriers based on block copolymers of l-proline and lactide: The effect of core crosslinking versus its pH-sensitivity on their cellular uptake10.1016/j.eurpolymj.2021.110572 ↗
37. Autoantibodies to a specific peptide epitope of human Hsp60 (ATVLA) with homology to Helicobacter pylori HspB in H. pylori-infected patients10.1111/apm.12925 ↗
38. Comparative study of structure and properties of thermal spray coatings using conventional and nanostructured hydroxyapatite powder, for applications in medical implants10.1016/j.surfcoat.2018.10.044 ↗
39. Cell death induced by hydroxyapatite on L929 fibroblast cells
40. Titanium-hydroxyapatite composites sintered at low temperature for tissue engineering: In vitro cell support and biocompatibility
41. Macrophage plasticity and polarization in tissue repair and remodelling10.1002/path.4133 ↗