RETRACTED: High-Sensitivity Biosensor Based on Glass Resonance PhC Cavities for Detection of Blood Component and Glucose Concentration in Human Urine
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Source abstract
Abstract
In this work, a novel structure of an all-optical biosensor based on glass resonance cavities with high detection accuracy and sensitivity in two-dimensional photon crystal is designed and simulated. The free spectral range in which the structure performs well is about FSR = 630 nm. This sensor measures the concentration of glucose in human urine. Analyses to determine the glucose concentration in urine for a normal range (0~15 mg/dL) and urine despite glucose concentrations of 0.625, 1.25, 2.5, 5 and 10 g/dL in the wavelength range 1.326404~1.326426 μm have been conducted. The detection range is RIU = 0.2 × 10−7. The average bandwidth of the output resonance wavelengths is 0.34 nm in the lowest case. In the worst case, the percentage of optical signal power transmission is 77% with an amplitude of 1.303241 and, in the best case, 100% with an amplitude of 1.326404. The overall dimensions of the biosensor are 102.6 µm2 and the sensitivity is equal to S = 1360.02 nm/RIU and the important parameter of the Figure of Merit (FOM) for the proposed biosensor structure is equal to FOM = 1320.23 RIU−1.
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Research context
OpenAlex topics: Photonic and Optical Devices · Photonic Crystals and Applications · Analytical Chemistry and Sensors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Faculty of Biology and Ecology, Yanka Kupala State University of Grodno, 230023 Grodno, Belarus
College of Technical Engineering, The Islamic University, Najaf 54001, Wasit, Iraq
Department of Dentistry, Kut University College, Kut 52001, Wasit, Iraq
Women Medical Officer Punjab Health Department, Faisalabad 38000, Pakistan
Institute of Pharmacy, Sechenov First Moscow State Medical University, 8 Trubetskaya St., Bldg. 2, 119991 Moscow, Russia
Federal Research Center of Nutrition, Biotechnology and Food Safety, Laboratory of Food Chemistry, 2/14 Ustyinsky Pr., 109240 Moscow, Russia
Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Laboratory of Biotoxicology, Pharmacognosy and Biological Valorization of Plants (LBPVBP), Faculty of Sciences, University of Saida—Dr Moulay Tahar, Saida 20000, Algeria
Faculty of Nursing, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok 10210, Thailand
Department of Chemical Engineering, School of Mining, Metallurgy and Chemical Engineering, University of Johannesburg, P.O. Box 17011, Johannesburg 2028, South Africa
Department of Biological and Chemical Engineering, Aarhus University, Nørrebrogade 44, 8000 Aarhus, Denmark
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