journal article·2023Open access

Numerical Procedure for Fractional HBV Infection with Impact of Antibody Immune

Sakda Noinang, Zulqurnain Sabir, Muhammad Asif Zahoor Raja, Soheil Salahshour, Wajaree Weera, Thongchai Botmart

Computers, Materials & Continua· Volume 74· Issue 2

Abstract

The current investigations are presented to solve the fractional order HBV differential infection system (FO-HBV-DIS) with the response of antibody immune using the optimization based stochastic schemes of the Levenberg-Marquardt backpropagation (LMB) neural networks (NNs), i.e., LMBNNs. The FO-HBV-DIS with the response of antibody immune is categorized into five dynamics, healthy hepatocytes (H), capsids (D), infected hepatocytes (I), free virus (V) and antibodies (W). The investigations for three different FO variants have been tested numerically to solve the nonlinear FO-HBV-DIS. The data magnitudes are implemented 75% for training, 10% for certification and 15% for testing to solve the FO-HBV-DIS with the response of antibody immune. The numerical observations are achieved using the stochastic LMBNNs procedures for soling the FO-HBV-DIS with the response of antibody immune and comparison of the results is presented through the database Adams-Bashforth-Moulton approach. To authenticate the validity, competence, consistency, capability and exactness of the LMBNNs, the numerical presentations using the mean square error (MSE), error histograms (EHs), state transitions (STs), correlation and regression are accomplished.
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Research context

OpenAlex topics: Fractional Differential Equations Solutions · Mathematical and Theoretical Epidemiology and Ecology Models · Advanced Control Systems Design

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