journal article·2021Open access

Residual U-Network for Breast Tumor Segmentation from Magnetic Resonance Images

Ishu Anand, Himani Negi, Deepika Kumar, Mamta Mittal, Tai-hoon Kim, Sudipta Roy

Computers, Materials & Continua· Volume 67· Issue 3

Abstract

Breast cancer positions as the most well-known threat and the main source of malignant growth-related morbidity and mortality throughout the world. It is apical of all new cancer incidences analyzed among females. Two features substantially influence the classification accuracy of malignancy and benignity in automated cancer diagnostics. These are the precision of tumor segmentation and appropriateness of extracted attributes required for the diagnosis. In this research, the authors have proposed a ResU-Net (Residual U-Network) model for breast tumor segmentation. The proposed methodology renders augmented, and precise identification of tumor regions and produces accurate breast tumor segmentation in contrast-enhanced MR images. Furthermore, the proposed framework also encompasses the residual network technique, which subsequently enhances the performance and displays the improved training process. Over and above, the performance of ResU-Net has experimentally been analyzed with conventional U-Net, FCN8, FCN32. Algorithm performance is evaluated in the form of dice coefficient and MIoU (Mean Intersection of Union), accuracy, loss, sensitivity, specificity, F1score. Experimental results show that ResU-Net achieved validation accuracy & dice coefficient value of 73.22% & 85.32% respectively on the Rider Breast MRI dataset and outperformed as compared to the other algorithms used in experimentation.
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Research context

OpenAlex topics: AI in cancer detection · Brain Tumor Detection and Classification · Medical Image Segmentation Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (62)

Show source-provided references
1. Breast cancer in the world: Incidence and mortality
2. Breast cancer as global health concern10.1016/j.canep.2009.10.003 ↗
3. Boyle · World Cancer Report · 2008
4. Joy · Saving Women’s Lives: Strategies for Improving Breast Cancer Detection and Diagnosis · 2005
5. Screening for breast cancer: U.S. preventive services task force recommendation statement10.7326/M15-2886 ↗
6. Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population based screening program10.1148/radiol.12121373 ↗
7. American cancer society guidelines for breast screening with MRI as an adjunct to mammography
8. Inflammatory breast cancer: PET/CT, MRI, mammography, and sonography findings10.1007/s10549-007-9671-z ↗
9. MRI evaluation of pathologically complete response and residual tumors in breast cancer after neoadjuvant chemotherapy10.1002/cncr.23130 ↗
10. The impact of arterial input function determination variations on prostate dynamic contrast-enhanced magnetic resonance imaging pharmacokinetic modeling10.18383/j.tom.2015.00184 ↗
11. MRI in the evaluation of breast cancer patient response to neoadjuvant chemotherapy: Predictive factors for breast conservative surgery
12. SegNet: A deep convolutional encoder–decoder architecture for robust semantic pixel-wise labelling10.1109/TPAMI.2016.2644615 ↗
13. Fully convolutional networks for semantic segmentation10.1109/TPAMI.2016.2572683 ↗
14. Learning deconvolution network for semantic segmentation
15. Multi-task deep learning for fine-grained classification and grading in breast cancer histopathological images10.1007/s11042-018-6970-9 ↗
16. Deep convolutional neural networks for breast cancer histology image analysis10.1007/978-3-319-93000-8_83 ↗
17. An improved salient object detection algorithm combining background and foreground connectivity for brain image analysis10.1016/j.compeleceng.2018.08.018 ↗
18. Detection and characterization of MRI breast lesions using deep learning10.1016/j.diii.2019.02.008 ↗
19. U-net: Convolutional networks for biomedical image segmentation10.1007/978-3-319-24574-4_28 ↗
20. Going deeper with convolutions
21. Imagenet classification with deep convolutional neural networks10.1145/3065386 ↗
22. DeCAF: A deep convolutional activation feature for generic visual recognition
23. K. Simonyan and A. Zisserman, “Very deep convolutional networks for large-scale image recognition,” arXiv preprint arXiv: 1409.1556, 2014.
24. Combining fully convolutional and recurrent neural networks for 3D biomedical image segmentation
25. Joint sequence learning and cross-modality convolution for 3D biomedical segmentation
26. 3D U-net: Learning dense volumetric segmentation from sparse annotation10.1007/978-3-319-46723-8_49 ↗
27. V-net: Fully convolutional neural networks for volumetric medical image segmentation
28. Semantic object classes in video: A high-definition ground truth database10.1016/j.patrec.2008.04.005 ↗
29. Fully automatic breast segmentation in 3D breast MRI
30. Accurate segmentation of breast tumors in ultrasound images using a custom-made active contour model and signal-to-noise ratio variations
31. Deep neural networks segment neuronal membranes in electron microscopy images
32. Automated breast segmentation of fat and water MR images using dynamic programming10.1016/j.acra.2014.09.015 ↗
33. Performance of a fully automatic lesion detection system for breast DCE-MRI10.1002/jmri.22680 ↗
34. Breast segmentation in MRI via U-net deep convolutional neural networks
35. Automated segmentation of breast in 3-D MR images using a robust atlas10.1109/TMI.2014.2347703 ↗
36. A fully automatic algorithm for segmentation of the breasts in DCE-MR images
37. Multi-planar 3D breast segmentation in MRI via deep convolutional neural networks10.1016/j.artmed.2019.101781 ↗
38. Feature selection for intrusion detection system using ant colony optimization
39. Segmentation of the pectoral muscle in breast MRI using atlas-based approaches10.1007/978-3-642-33418-4_46 ↗
40. Brain tumor segmentation with deep neural networks10.1016/j.media.2016.05.004 ↗
41. Edge detection in MRI brain tumor images based on fuzzy C-means clustering10.1016/j.procs.2018.08.069 ↗
42. An efficient edge detection approach to provide better edge connectivity for image analysis10.1109/ACCESS.2019.2902579 ↗
43. ImageNet: A large-scale hierarchical image database
44. Deep residual learning for image recognition
45. A computational approach to edge detection10.1109/TPAMI.1986.4767851 ↗
46. Deep learning based enhanced tumor segmentation approach for MR brain images10.1016/j.asoc.2019.02.036 ↗
47. L. C. Chen, G. Papandreou, K. Murphy and A. L. Yuille, “Semantic image segmentation with deep convolutional nets and fully connected Crfs,” arXiv preprint arXiv: 1412.7062, 2014.
48. Kernel based method for segmentation and modeling of magnetic resonance images
49. Mixed pixel decomposition based on extended fuzzy clustering for single spectral value remote sensing images10.1007/s12524-019-00946-2 ↗
50. Road extraction by deep residual U-net10.1109/LGRS.2018.2802944 ↗
51. B. Kayalibay, G. Jensen and P. van der Smagt, “CNN-based segmentation of medical imaging data,” arXiv preprint arXiv: 1701.03056, 2017.
52. An RDAU-NET model for lesion segmentation in breast ultrasound images10.1371/journal.pone.0221535 ↗
53. VoxResNet: Deep voxelwise residual networks for volumetric brain segmentation from 3D MR images10.1016/j.neuroimage.2017.04.041 ↗
54. Data from RIDER-breast-MRI, “The cancer imaging archive,” 2015. https://wiki.cancerimagingarchive.net/display/Public/RIDER+Breast+MRI.
55. Evaluating the impact of intensity normalization on MR image synthesis
56. A. Dosovitskiy, J. T. Springenberg and T. Brox, “Unsupervised feature learning by augmenting single images,” arXiv preprint arXiv: 1312.5342, 2013.
57. Deep Image: Scaling up image recognition
58. Batch normalization: Accelerating deep network training by reducing internal covariate shift
59. Adam: A method for stochastic optimization
60. Measures of the amount of ecologic association between species10.2307/1932409 ↗
61. Simultaneous detection and segmentation10.1007/978-3-319-10584-0_20 ↗
62. UCSB Bio-segmentation dataset, https://bioimage.ucsb.edu/research/bio-segmentation.