EMU-Net: Automatic Brain Tumor Segmentation and Classification Using Efficient Modified U-Net
Source abstract
Abstract
Tumor segmentation is a valuable tool for gaining insights into tumors and improving treatment outcomes. Manual segmentation is crucial but time-consuming. Deep learning methods have emerged as key players in automating brain tumor segmentation. In this paper, we propose an efficient modified U-Net architecture, called EMU-Net, which is applied to the BraTS 2020 dataset. Our approach is organized into two distinct phases: classification and segmentation. In this study, our proposed approach encompasses the utilization of the gray-level co-occurrence matrix (GLCM) as the feature extraction algorithm, convolutional neural networks (CNNs) as the classification algorithm, and the chi-square method for feature selection. Through simulation results, the chi-square method for feature selection successfully identifies and selects four GLCM features. By utilizing the modified U-Net architecture, we achieve precise segmentation of tumor images into three distinct regions: the whole tumor (WT), tumor core (TC), and enhanced tumor (ET). The proposed method consists of two important elements: an encoder component responsible for down-sampling and a decoder component responsible for up-sampling. These components are based on a modified U-Net architecture and are connected by a bridge section. Our proposed CNN architecture achieves superior classification accuracy compared to existing methods, reaching up to 99.65%. Additionally, our suggested technique yields impressive Dice scores of 0.8927, 0.9405, and 0.8487 for the tumor core, whole tumor, and enhanced tumor, respectively. Ultimately, the method presented demonstrates a higher level of trustworthiness and accuracy compared to existing methods. The promising accuracy of the EMU-Net study encourages further testing and evaluation in terms of extrapolation and generalization.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Brain Tumor Detection and Classification · Advanced Neural Network Applications · Radiomics and Machine Learning in Medical Imaging
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (58)
Show source-provided references
1. Multi-classification of brain tumor MRI images using deep convolutional neural network with fully optimized framework10.1007/s40998-021-00426-9 ↗
2. Recent advances in the molecular understanding of glioblastoma10.1007/s11060-011-0793-0 ↗
3. Deep learning for brain tumor segmentation: A survey of state-of-the-art10.3390/jimaging7020019 ↗
4. Dual-force convolutional neural networks for accurate brain tumor segmentation10.1016/j.patcog.2018.11.009 ↗
5. State of the art survey on MRI brain tumor segmentation10.1016/j.mri.2013.05.002 ↗
6. Chen · Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries · 2019 · 358
7. Deep learning in radiology: An overview of the concepts and a survey of the state of the art with focus on MRI10.1002/jmri.26534 ↗
8. 3D U-Net: Learning dense volumetric segmentation from sparse annotation
9. Application of U-Net and optimized clustering in medical image segmentation: A review10.32604/cmes.2023.025499 ↗
10. Brain tumor segmentation using convolutional neural networks in MRI images10.1109/TMI.2016.2538465 ↗
11. Mu-Net: Multi-path upsampling convolution network for medical image segmentation10.32604/cmes.2022.018565 ↗
12. Brain tumor segmentation using cascaded deep convolutional neural network
13. Brain tumor segmentation in multi-spectral MRI using convolutional neural networks (CNN)10.1002/jemt.22994 ↗
14. Wang · Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries · 2019 · 61
15. Brain tumor segmentation using convolutional neural networks in MRI images10.1007/s10916-019-1416-0 ↗
16. An enhancement of deep learning algorithm for brain tumor segmentation using kernel based CNN with M-SVM10.1007/s10916-019-1223-7 ↗
17. AFPNet: A 3D fully convolutional neural network with atrous-convolution feature pyramid for brain tumor segmentation via MRI images10.1016/j.neucom.2020.03.097 ↗
18. DeepSeg: Deep neural network framework for automatic brain tumor segmentation using magnetic resonance flair images10.1007/s11548-020-02186-z ↗
19. Deriving tumor detection models using convolutional neural networks from MRI of human brain scans10.1007/s41870-020-00438-4 ↗
20. Brain tumor segmentation with deep convolutional symmetric neural network10.1016/j.neucom.2019.01.111 ↗
21. Vijh · Data Visualization and Knowledge Engineering: Spotting Data Points with Artificial Intelligence · 2020 · 32 · 17110.1007/978-3-030-25797-2_8 ↗
22. Combining wavelet texture features and deep neural network for tumor detection and segmentation over MRI10.1515/jisys-2017-0090 ↗
23. Brain tumor classification using gray level co-occurrence matrix and convolutional neural network10.22146/ijeis.34713 ↗
24. Brain tumor detection system based on sending email using gray level co-occurrence matrix and back-propagation neural network
25. Recurrent residual convolutional neural network based on U-Net (R2U-Net) for medical image segmentation
26. Road extraction by deep residual U-Net10.1109/LGRS.2018.2802944 ↗
27. Fully convolutional neural networks for volumetric medical image segmentation
28. Auto-context convolutional neural network (auto-net) for brain extraction in magnetic resonance imaging10.1109/TMI.2017.2721362 ↗
29. UNet++: Redesigning skip connections to exploit multiscale features in image segmentation10.1109/TMI.2019.2959609 ↗
30. Prostate segmentation using 2D bridged U-Net
31. Brain tumor segmentation and grading of lowergrade glioma using deep learning in MRI images10.1016/j.compbiomed.2020.103758 ↗
32. S. Bakas, M. Reyes, A. Jakab, S. Bauer, M. Rempfler et al., “Identifying the best machine learning algorithms for brain tumor segmentation,” arXiv preprint arXiv:1811.02629, 2018.
33. The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS)10.1109/TMI.2014.2377694 ↗
34. Hybrid between ontology and quantum particle swarm optimization for segmenting noisy plant disease image10.22266/ijies2019.1031.30 ↗
35. A novel deep learning model to detect COVID-19 based on wavelet features extracted from Mel-scale spectrogram of patients’ cough and breathing sounds10.1016/j.imu.2022.101049 ↗
36. A new model to detect COVID-19 coughing and breathing sound symptoms classification from CQT and Mel spectrogram image representation using deep learning10.14569/IJACSA.2022.0130869 ↗
37. Molecular property prediction of modified gedunin using machine learning10.3390/molecules28031125 ↗
38. Image texture feature extraction using GLCM approach
39. Automated classification of lung cancer subtypes using deep learning and CT-scan based radiomic analysis10.3390/bioengineering10060690 ↗
40. Sudre · Deep Learning in Medical Image Analysis and Multimodal Learning for Clinical Decision Support · 2017 · 240
41. Simultaneous fault diagnosis based on multiple kernel support vector machine in nonlinear dynamic distillation column10.1002/ese3.1058 ↗
42. A feature extraction using cnn for peripheral blood cells recognition
43. Ronneberger · Medical Image Computing and Computer-Assisted Intervention-MICCAI · 2015 · 234
44. Fully convolutional networks for semantic segmentation10.1109/TPAMI.2016.2572683 ↗
45. Brain tumor image segmentation via asymmetric/symmetric UNet based on two-pathway-residual blocks10.1016/j.bspc.2021.102841 ↗
46. Yuan · Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries · 2021 · 285
47. Efficient MRI brain tumor segmentation using multi-resolution encoder-decoder networks
48. Isensee · Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries · 2021 · 118
49. Lyu · Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries · 2021 · 435
50. Brain tumor segmentation with a muti-pathway ResNet based UNet10.1007/s10723-021-09590-y ↗
51. ME-Net: Multi encoder net framework for brain tumor segmentation10.1002/ima.22571 ↗
52. Colman · Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries · 2021 · 410
53. Attention-guided version of 2D UNet for automatic brain tumor segmentation
54. Automated MRI based pipeline for segmentation and prediction of grade, IDH mutation and 1p19q co-deletion in glioma10.1016/j.compmedimag.2020.101831 ↗
55. Medical image segmentation using squeeze-and-expansion transformers
56. A deep learning framework integrating mri image preprocessing methods for brain tumor segmentation and classification
57. Glioma grading on conventional mr images: A deep learning study with transfer learning10.3389/fnins.2018.00804 ↗
58. Multimodal disentangled variational autoencoder with game theoretic interpretability for glioma grading10.1109/JBHI.2021.3095476 ↗