Applying ANN, ANFIS, and LSSVM Models for Estimation of Acid Solvent Solubility in Supercritical CO2

In the present work, a novel machine learning computational investigation is carried out to accurately predict the solubility of different acids in supercritical carbon dioxide. Four different machine learning algorithms of radial basis function, multi-layer perceptron (MLP), artificial neural networks (ANN), least squares support vector machine (LSSVM) and adaptive neuro-fuzzy inference system (ANFIS) are used to model the solubility of different acids in carbon dioxide based on the temperature, pressure, hydrogen number, carbon number, molecular weight, and the dissociation constant of acid. To evaluate the proposed models, different graphical and statistical analyses, along with novel sensitivity analysis, are carried out. The present study proposes an efficient tool for acid solubility estimation in supercritical carbon dioxide, which can be highly beneficial for engineers and chemists to predict operational conditions in industries.