Hep-Pred: Hepatitis C Staging Prediction Using Fine Gaussian SVM
Source abstract
Abstract
Hepatitis C is a contagious blood-borne infection, and it is mostly asymptomatic during the initial stages. Therefore, it is difficult to diagnose and treat patients in the early stages of infection. The disease’s progression to its last stages makes diagnosis and treatment more difficult. In this study, an AI system based on machine learning algorithms is presented to help healthcare professionals with an early diagnosis of hepatitis C. The dataset used for our Hep-Pred model is based on a literature study, and includes the records of 1385 patients infected with the hepatitis C virus. Patients in this dataset received treatment dosages for the hepatitis C virus for about 18 months. A former study divided the disease into four main stages. These stages have proven helpful for doctors to analyze the liver’s condition. The traditional way to check the staging is the biopsy, which is a painful and time-consuming process. This article aims to provide an effective and efficient approach to predict hepatitis C staging. For this purpose, the proposed technique uses a fine Gaussian SVM learning algorithm, providing 97.9% accurate results.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Liver Disease Diagnosis and Treatment · Hepatitis C virus research · Artificial Intelligence in Healthcare
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (41)
Show source-provided references
1. World Health Organization, “Hepatitis C [Hepatitis C],” WHO, 2020. [Online]. Available: https://www. who.int/news-room/fact-sheets/detail/hepatitis-c#:~:text=Key facts,major cause of liver cancer [Accessed: 30-Aug-2020].
2. Evolutionary-driven support vector machines for determining the degree of liver fibrosis in chronic hepatitis C10.1016/j.artmed.2010.06.002 ↗
3. Hepatitis C virus: A global view10.4254/wjh.v7.i26.2676 ↗
4. Noninvasive measurements predict liver fibrosis well in hepatitis C virus patients after direct-acting antiviral therapy10.1007/s10620-019-05886-y ↗
5. QSAR models for phosphoramidate prodrugs of 2’-methylcytidine as inhibitors of hepatitis C virus based on PSO boosting10.1111/j.1747-0285.2011.01236.x ↗
6. Singh · Advances in Biomedical Engineering and Technology · 2021 · 16110.1007/978-981-15-6329-4_15 ↗
7. Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C10.1053/j.gastro.2011.02.058 ↗
8. Artificial intelligence versus clinicians in disease diagnosis: Systematic review
9. Diagnostic value of serum markers of connective tissue turnover for predicting histological staging and grading in patients with chronic hepatitis C10.1007/s005350170084 ↗
10. Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C10.1002/hep.20717 ↗
11. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C10.1053/jhep.2003.50346 ↗
12. Accuracy of hyaluronic acid level for predicting liver fibrosis stages in patients with hepatitis C virus10.1186/1476-5926-4-6 ↗
13. A novel model based on non invasive methods for prediction of liver fibrosis
14. Healthline, “What are the stages of hepatitis C?-HepatitisC.net,” Healthline Media, 2018. [Online]. Available: https://hepatitisc.net/living/what-are-the-stages-of-hepatitis-c/ [Accessed: 15-Aug-2020].
15. MHealth Lab, “Early detection, early treatment for hepatitis C,” MHealth Lab, 2016. [Online]. Available: https://labblog.uofmhealth.org/rounds/early-detection-early-treatment-for-hepatitis-c [Accessed: 20-Aug-2020].
16. Hepatitis C virus: Screening, diagnosis, and interpretation of laboratory assays10.4103/0973-6247.126683 ↗
17. Artificial intelligence in healthcare: Past, present and future10.1136/svn-2017-000101 ↗
18. Machine learning models to predict disease progression among veterans with hepatitis C virus10.1371/journal.pone.0208141 ↗
19. Liver fibrosis staging with combination of APRI and FIB-4 scoring systems in chronic hepatitis C as an alternative to transient elastography
20. Novel non-invasive score to predict cirrhosis in the era of hepatitis C elimination: A population study of ex-substance users in Singapore10.1016/j.hbpd.2018.12.002 ↗
21. Simple scoring system for prediction of hepatocellular carcinoma occurrence after hepatitis C virus eradication by direct‐acting antiviral treatment: All kagawa liver disease group study
22. Hepatitis C virus (HCV) prediction by machine learning techniques
23. Fahim, rs2267531, a promoter SNP within glypican-3 gene in the X chromosome, is associated with hepatocellular carcinoma in Egyptians10.1038/s41598-019-43376-3 ↗
24. Neural-network analysis of socio-medical data to identify predictors of undiagnosed hepatitis C virus infections in Germany (DETECT)10.1186/s12967-019-1832-4 ↗
25. J. Bresnick, “Predictive analytics identify high risk Hepatitis C patients,” Health IT Analytics, 2015. [Online]. Available: https://healthitanalytics.com/news/predictive-analytics-identify-high-risk-hepatitis-c- patients/ [Accessed: 15-Oct-2020].
26. Association between visceral obesity and hepatitis C infection stratified by gender: A cross-sectional study in Taiwan10.1136/bmjopen-2017-017117 ↗
27. Body mass index is associated with age-at-onset of HCV infected hepatocellular carcinoma patients10.3748/wjg.v17.i7.914 ↗
28. An analysis of hepatitis C virus prediction using different data mining techniques
29. Performance of machine learning approaches on prediction of esophageal varices for Egyptian chronic hepatitis C patients10.1016/j.imu.2019.100267 ↗
30. Accurate prediction of advanced liver fibrosis using the decision tree learning algorithm in chronic hepatitis c Egyptian patients10.1155/2016/2636390 ↗
31. Noninvasive biomarkers predict improvement in liver fibrosis after successful generic DAAs based therapy of chronic hepatitis C in Egypt10.1016/j.cegh.2020.04.011 ↗
32. Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis10.1016/j.clinre.2019.11.005 ↗
33. Albumin-bilirubin score indicates liver fibrosis staging and prognosis in patients with chronic hepatitis C10.1111/hepr.13333 ↗
34. Machine learning prediction models for diagnosing hepatocellular carcinoma with HCV-related chronic liver disease10.1016/j.cmpb.2020.105551 ↗
35. The utility of retinol-binding protein 4 in predicting liver fibrosis in chronic hepatitis C patients in response to direct-acting antivirals10.2147/CEG.S229689 ↗
36. Liver stiffness measurement by transient elastography can predict outcome after hepatic resection for hepatitis C virus-induced hepatocellular carcinoma
37. Fibrosis index based on 4 factors (fib-4) predicts liver cirrhosis and hepatocellular carcinoma in chronic hepatitis C virus (HCV) patients10.12659/MSM.918784 ↗
38. Brain tumor analysis empowered with deep learning: A review, taxonomy, and future challenges10.3390/brainsci10020118 ↗
39. A comparison of transfer learning performance versus health experts in disease diagnosis from medical imaging10.1109/ACCESS.2020.3004766 ↗
40. Bone age assessment empowered with deep learning: A survey, open research challenges and future directions10.3390/diagnostics10100781 ↗
41. A comparative systematic literature review on knee bone reports from MRI, X-rays and CT scans using deep learning and machine learning methodologies10.3390/diagnostics10080518 ↗