Metal–Organic Framework‐Based Composites for Wearable Electrochemical Sensing in Healthcare: A Review

In recent years, owing to hectic work schedules, people have struggled to continuously monitor their health. Present sensing technologies face several challenges, including rigidity for fixed applications, wired connections, and standard power source challenges for continuous monitoring of various analytes. In contrast, sensors integrated with flexible and biocompatible substrates have shown promising results for continuously monitoring analyte concentrations with high selectivity and sensitivity. In addition, recent research on electrochemical wearable sensors based on metal–organic frameworks (MOFs) has opened new horizons for improving sensor accuracy. In this review, we present recent advancements in the continuous monitoring of health using wearable electrochemical sensors based on MOFs nanocomposites. A detailed discussion is presented on the critical design considerations, substrate selection, and various electrodes, including screen‐printed electrodes, hydrogels, and fibers, used in continuous monitoring systems. We highlight the key properties of MOFs, the integration of MOFs with other conductive materials for superior analyte detection, and the application of wireless data acquisition and microfluidic systems for real‐time monitoring of analytes. Finally, we discuss the challenges and future outlook of wearable electrochemical sensors.