Front Cover: Kinetics of Drug Release via Nicardipine Hydrochloride‐loaded Carboxymethyl Cellulose/Poly(D,L‐lactic‐co‐glycolic acid) Nanocarriers Using a Contemporary Emulsion Process (ChemNanoMat 12/2020)
Source abstract
Abstract
Nicardipine hydrochloride-loaded carboxymethyl cellulose/poly(D,L-lactic-co-glycolic acid) nanocarriers were synthesized using a contemporary double emulsion process. The NCH-CMC/PLGA nanocarriers can prolong the drug concentration and protect the drug from hydrolysis throughout a period of 16 days. The drug release kinetics indicated that the model followed the Korsmeyer-peppas equation, leading to a combination of drug diffusion and polymer erosion. These nanocarriers could be an effective drug-delivery agent for calcium channel blockers. More information can be found in the Full Paper by Narumol Kreua-ongarjnukool, Sorayouth Chumnanvej et al.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced Drug Delivery Systems · Nanoparticle-Based Drug Delivery · Drug Solubulity and Delivery Systems
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Industrial Chemistry Faculty of Applied Science King Mongkut's University of Technology North Bangkok Bangkok Thailand 1518 Pracharat 1 Road, Wongsawang, Bangsue Bangkok 10800
Surgery Department Faculty of Medicine Ramathibodi Hospital Mahidol University, Bangkok Thailand 270 Thanon Rama VI, Thung Phaya Thai, Ratchathewi Bangkok 10400
References
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