Front Cover: Organosilica Nanoparticles for Gemcitabine Monophosphate Delivery in Cancer Cells (ChemNanoMat 7/2019)
Source abstract
Abstract
Two kinds of organosilica nanoparticles based on ionosilicas or neutral tertiary amino compounds have been loaded with gemcitabine monophosphate and are able to deliver the drug in cancer cells due to phosphate exchange or pH stimulus. Both nanoparticles are endocytosed in cancer cells, as monitored by fluorescence microscopy, and are very efficient, leading to 60% cancer cell death. These nanoparticles are therefore promising vectors for nanomedicine applications against tumors. More information can be found in the Full Paper by Magali Gary-Bobo, Jean-Olivier Durand, Peter Hesemann et al. on page 888 in Issue 7, 2019 (DOI: 10.1002/cnma.201900202).
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institut des Biomolécules Max Mousseron UMR 5247 CNRS, UM-Faculté de Pharmacie Avenue Charles Flahault 34093 Montpellier cedex 05 France
NanoMedSyn Institut des Biomolécules Max Mousseron UMR 5247 CNRS, UM-Faculté de Pharmacie Avenue Charles Flahault 34093 Montpellier cedex 05 France
Institut Charles Gerhardt Montpellier UMR-5253 CNRS-UM-ENSCM cc 1701 Place Eugène Bataillon 34095 Montpellier cedex 05 France
References
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