Cover Feature: Protein Corona Formation on Magnetic Nanoparticles Conjugated with Luminescent Europium Complexes (ChemNanoMat 12/2018)

Magneto-luminescent nanobioprobes based on Fe3O4 conjugated to europium complexes interact with human blood plasma and establish a nanoparticle/biological interfaces, leading to the formation of protein coronas. The bio-nano interface comprises the dynamic physicochemical interactions, kinetics and thermodynamic exchanges between nanoparticles surfaces and the surfaces of biological components (proteins). These nanoparticles can be rapidly magnetically confined, retaining the narrow emission lines from europium (III) ion after protein corona formation, providing a new perspective to develop multifunctional nanoprobe for ex-vivo detection of proteins in biological medium (e.g., blood plasma). More information can be found in the Communication by Latif U. Khan, Diego Stéfani Teodoro Martinez et al. on page 1202 in Issue 12, 2018 (DOI: 10.1002/cnma.201800358).