DataVXChemNanoMatPaper
journal article·2016-01Open access

Inside Back Cover: Design Principles for Peptide‐Amphiphile‐Induced Liposomal Receptor‐Targeting with Intracellular Thermosensitivity (ChemNanoMat 1/2016)

Kamlesh Shroff, Dalong Liu, Rajagopal N. Aravalli, Colleen L. Forster, Thomas Pengo, Mark A. Sanders, Emad S. Ebbini, Efrosini Kokkoli

ChemNanoMat· Volume 2· Issue 1
Publisher pageOpen full text
Source abstract

Abstract

Stealth liposomes were combined with single-tail peptide-amphiphiles that provided receptor-specific binding and cell internalization while also inducing the thermosensitive properties of the liposomes. The resulting peptide-functionalized liposomes, featured on the Inside Back Cover, outperformed commercially available thermosensitive formulations in terms of cell binding and intracellular temperature-triggered release in vitro, and showed increased release in vivo after treating the liver of a mouse with mild hyperthermia via a dual-mode ultrasound array. More details can be found in the Communication by E. S. Ebbini, E. Kokkoli et al. on page 42 in Issue 1, 2016 (DOI: 10.1002/cnma.201500138).
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Chemical Synthesis and Analysis · Nanoparticle-Based Drug Delivery · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemical Engineering and Materials Science University of Minnesota Minneapolis MN 55455 USA

Department of Electrical and Computer Engineering University of Minnesota Minneapolis MN 55455 USA

Department of Radiology University of Minnesota Minneapolis MN 55455 USA

BioNet, Clinical and Translational Science Institute University of Minnesota Minneapolis MN 55455 USA

University of Minnesota Informatics Institute University of Minnesota Minneapolis MN 55455 USA

University Imaging Centers University of Minnesota Minneapolis MN 55455 USA

References

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