DataVXChemNanoMatPaper
journal article·2019-06Open access

Front Cover: Supramolecular Self‐Assembly of DNA with a Cationic Polythiophene: From Polyplexes to Fibers (ChemNanoMat 6/2019)

Maxime Leclercq, Jenifer Rubio‐Magnieto, Danahe Mohammed, Sylvain Gabriele, Laurent Leclercq, Hervé Cottet, Sébastien Richeter, Sébastien Clément, Mathieu Surin

ChemNanoMat· Volume 5· Issue 6
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Source abstract

Abstract

Cationic polythiophenes (CPTs) constitute an interesting class of π-conjugated polymers for DNA sensing and delivery. Here, the supramolecular self-assembly of a poly[3-(6’-(trimethylphosphonium)hexyl)thiophene-2,5-diyl] and various types of DNA is explored. In aqueous solutions, polyplex formation occurs with hydrodynamic radii between a few nm to around 25 nm. Chirality induction occurs from DNA to the achiral polymer, with important chiroptical signals in the spectral range of the latter. When solutions are deposited on surfaces, aggregation yield long dendritic fibers that can extend over tens μm with long DNA yield long fiber, with homogeneous fluorescence of the polymer. More information can be found in the Communication by Hervé Cottet, Sébastien Clément, Mathieu Surin et al. on page 703 in Issue 6, 2019 (DOI: 10.1002/cnma.201900022).
Source: openalex_inverted_index · Quality: baseline

Research context

Polymers

OpenAlex topics: Polydiacetylene-based materials and applications · Dendrimers and Hyperbranched Polymers · RNA Interference and Gene Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Laboratory for Chemistry of Novel Materials Center for Innovation in Materials and Polymers University of Mons – UMONS 20 Place du Parc B-7000 Mons Belgium

Current address: Bioinspired Supramolecular Chemistry and Materials Group Departament de Química Inorgànica i Orgànica Universitat Jaume I Avda Sos Baynat s/n E-12071 Castelló Spain

Mechanobiology & Soft Matter Group Laboratoire Interfaces et Fluides Complexes Center for Innovation in Materials and Polymers University of Mons – UMONS 20 Place du Parc B-7000 Mons Belgium

Institut des Biomolécules Max Mousseron (IBMM) Université de Montpellier, CNRS, ENSCM Montpellier France

Institut Charles Gerhardt (ICGM), UMR 5253 CNRS-ENSCM-UM Université de Montpellier – CC1701, Place Eugène Bataillon F-34095 Montpellier Cedex 05 France

References

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