journal article·2019-09

Facile Formation of Stable Water‐Dispersed Luminescent Silicon Nanocrystals by Laser Processing in Liquid: Toward Fluorescent Labeling for Bio‐Imaging

Ze Yuan, Toshihiro Nakamura, Shanmugavel Chinnathambi, Yanbai Pu, Naoto Shirahata, Kiyoto Matsuishi

ChemNanoMat· Volume 5· Issue 9
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Abstract

Abstract We herein develop a facile formation process of a water‐dispersed red luminescent undecenoic acid‐functionalized silicon nanocrystal (UA‐F: Si‐nc) via pulsed laser irradiation of porous silicon (PSi) in an organic solvent. The formed UA‐F: Si‐nc has a high stability against pH changes in aqueous solution and photo‐irradiation in water without any multi‐step surface treatments. Such a robust aqueous surface protection of Si‐nc is caused by hydrophilic organic group terminations and subsequent surface protection of OH bonding. From the viability and in vitro bio‐imaging tests against Hela cells and A549 cells, we confirmed that UA‐F: Si‐nc has very low cytotoxicity due to the essential biocompatibility of silicon and remains exhibiting a bright red luminescence in the cells. Because of its high stability in water as well as biocompatibility, UA‐F: Si‐nc is expected to act as a fluorescent label of cellular imaging.
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Research context

OpenAlex topics: Silicon Nanostructures and Photoluminescence · Laser-Ablation Synthesis of Nanoparticles · Carbon and Quantum Dots Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Faculty of Pure and Applied Sciences University of Tsukuba Tsukuba Ibaraki 305-8573 Japan

Department of Electrical and Electronics Engineering Hosei University Tokyo 184-8584 Japan

WPI International Centre for Nanoarchitectonics (MANA) National Institute for Materials Science (NIMS) Namiki Tsukuba 305-0044 Japan

International Center for Young Scientists (ICYS) NIMS 1-2-1 Sengen Tsukuba 305-0047 Japan

Department of Basic Medicine School Qiqihar Medical University Qiqihar Heilongjiang 161006 China

PRESTO Japan Science and Technology Agency (JST) 4-1-8 Honcho Kawaguchi Saitama 332-0012 Japan

Funding

Ministry of Education, Culture, Sports, Science and Technology

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