Self Assembly through Sonication: An Expeditious and Green Approach for the Synthesis of Organic‐Inorganic Hybrid Nanopetals and their Application as Biocatalyst

Abstract The present study exhibits a facile method for the expeditious synthesis of organic‐inorganic hybrid nanoassemblies. Pseudomonas fluorescens lipase was immobilized on the nanoassembly and its application as a nanobiocatalyst was demonstrated. Scanning electron microscopy analysis depicted petal‐like morphology of the newly synthesized hybrid. The sonochemical method screened as a faster route for the synthesis of hybrid nanopetals with a marked increase in enzyme activity (15 folds). Furthermore, an additional treatment of the hybrid nanopetals with chemical modifiers likes 1‐ethyl‐3‐(3‐dimethylaminopropyl)‐carbodiimide (EDC) exhibited improved stability and reusability upto six cycles. A systematic investigation of the reaction parameters influencing the formation of lipase‐embedded hybrid nanopetals was done. In addition, the nanobiocatalytic potential of hybrid nanopetals was explored in the kinetic resolution of racemic secondary alcohols.