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journal article·2019-06Open access

Flexible and Stretchable PEDOT‐Embedded Hybrid Substrates for Bioengineering and Sensory Applications

Afsoon Fallahi, Serena Mandla, Thomas Kerr‐Phillip, Jungmok Seo, Raquel O. Rodrigues, Yasamin A. Jodat, Roya Samanipour, Mohammad Asif Hussain, Chang Kee Lee, Hojae Bae, Ali Khademhosseini, Jadranka Travas‐Sejdic, Su Ryon Shin

ChemNanoMat· Volume 5· Issue 6
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Source abstract

Abstract

Abstract Herein, we introduce a flexible, biocompatible, robust and conductive electrospun fiber mat as a substrate for flexible and stretchable electronic devices for various biomedical applications. To impart the electrospun fiber mats with electrical conductivity, poly(3,4‐ethylenedioxythiophene) (PEDOT), a conductive polymer, was interpenetrated into nitrile butadiene rubber (NBR) and poly(ethylene glycol)dimethacrylate (PEGDM) crosslinked electrospun fiber mats. The mats were fabricated with tunable fiber orientation, random and aligned, and displayed elastomeric mechanical properties and high conductivity. In addition, bending the mats caused a reversible change in their resistance. The cytotoxicity studies confirmed that the elastomeric and conductive electrospun fiber mats support cardiac cell growth, and thus are adaptable to a wide range of applications, including tissue engineering, implantable sensors and wearable bioelectronics.
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Research context

PolymersBiomaterials

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Conducting polymers and applications · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Engineering in Medicine Department of Medicine Brigham and Women's Hospital Harvard Medical School Boston MA 02139 USA

Harvard-MIT Division of Health Sciences and Technology Massachusetts Institute of Technology Cambridge MA 02139 USA

Institute of Biomaterials and Biomedical Engineering University of Toronto Toronto, Ontario Canada

Polymer Electronics Research Centre (PERC) School of Chemical Sciences The University of Auckland 23 Symonds Street Auckland New Zealand

The MacDiarmid Institute for Advanced Materials and Nanotechnology New Zealand

Centre for Biomaterials Biomedical Research Institute Korea Institute of Science and Technology 14 Hwarang-ro, Seongbuk-gu Seoul 02792 Republic of Korea

Laboratory of Separation and Reaction Engineering Laboratory of Catalysis and Materials (LSRE-LCM) Faculdade de Engenharia Universidade do Porto, Rua Dr. Roberto Frias 4200-465 Porto Portugal

Department of Mechanical Engineering Stevens Institute of Technology New Jersey USA

School of Engineering University of British Columbia Okanagan, BC Canada

Department of Electrical and Computer Engineering Faculty of Engineering King Abdulaziz University P.O. Box 80204 Jeddah 21589 Saudi Arabia

Korea Packaging Center Korea Institute of Industrial Technology Bucheon Republic of Korea

KU Convergence Science and Technology Institute Department of Stem Cell and Regenerative Biotechnology Konkuk University Seoul 05029 Republic of Korea

Department of Bioengineering Department of Chemical and Biomolecular Engineering Henry Samueli School of Engineering and Applied Sciences University of California-Los Angeles Los Angeles CA 90095 USA

Department of Radiology David Geffen School of Medicine University of California-Los Angeles Los Angeles CA 90095 USA

Funding

National Institutes of Health · Qatar national Research Fund

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