Polydopamine‐Mediated Surface Functionalization of Exosomes
Source abstract
Abstract
Abstract Exosomes are cell‐derived extracellular vesicles that hold promise for diagnosis and therapy. The surface characteristics of exosomes dictate their biological fate and are therefore important for various applications, however surface modification strategies are generally either limited in scope or require complex equipment or experimental procedures. Herein, we employ a simple and fast method to control the surface properties of exosomes via polydopamine coating. Specifically, the polydopamine coating allowed for tailorable functionalization via secondary reactions, which opens exciting avenues for the application of exosomes.
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Research context
OpenAlex topics: Extracellular vesicles in disease · Polymer Surface Interaction Studies · Dendrimers and Hyperbranched Polymers
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Materials Engineering, Graduate School of Engineering The University of Tokyo 7-3-1 Hongo Bunkyo-ku 113-8656 Japan
Center for Disease Biology and Integrative Medicine, Graduate School of Medicine The University of Tokyo 7-3-1 Hongo Bunkyo-ku 113-8656 Japan
Funding
Mitsubishi Foundation · Asahi Glass Foundation · University of Tokyo · Ministry of Education, Culture, Sports, Science and Technology · Japan Society for the Promotion of Science
References (22)
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