Biomimic Redox Driven Ion Transportation in Smart Nanochannels
Source abstract
Abstract
Hydrogen peroxide (H 2 O 2 ) affects biological processes by producing cellular signaling to regulate redox reactions in live cells. By redox signaling, Cytochrome C (Cyt C) in mammalian cells is especially distinguishable for H 2 O 2 in controlling ion transportation in biological ion channels. To mimic the mechanism for redox-driven in biology, we modified Cyt C, which could bind H 2 O 2, on polymer conical nanochannels to form a redox-driven nanosystem. The influence of the different H 2 O 2 concentrations on the ion transportation property in the redox-driven nanosystem is investigated and discussed. The theoretical model of this nanosystem based on the Poisson and Nernst–Planck equations is in good agreement with the experimental data. Accordingly, we constitute a biomimetic reversible and repeatable redox-driven smart nanogating system, monitoring the ion transportation process.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanopore and Nanochannel Transport Studies · Fuel Cells and Related Materials · Advanced biosensing and bioanalysis techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, No. 37, Xueyuan Road, Haidian District, Beijing 100191, P. R. China
Funding
Ministry of Education of the People's Republic of China · National Natural Science Foundation of China
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