Size and Compositional Effects on Contrast Efficiency of Functionalized Superparamagnetic Nanoparticles at Ultralow and Ultrahigh Magnetic Fields
Source abstract
Abstract
Magnetic resonance imaging (MRI) systems at ultralow and ultrahigh field have been developed for biomedical imaging. We synthesized and functionalized superparamagnetic (SPM) nanoparticles (NPs) and studied the spin–lattice ( T 1 ) and spin–spin ( T 2 ) relaxation time of protons in water surrounding these NPs at ultralow and at ultrahigh magnetic fields. In these fields, size and compositional effects of SPM NPs were observed contributing to the spin–lattice ( r 1 ) and spin–spin ( r 2 ) relaxivities as well as r 2 / r 1 ratios. These results reveal the relationship between magnetic characteristics of SPM NPs and relaxation behavior of water proton at ultralow or ultrahigh field.
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Research context
OpenAlex topics: Advanced NMR Techniques and Applications · Atomic and Subatomic Physics Research · Electron Spin Resonance Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
National Engineering Research Center for Biomaterials, Sichuan University, 610064 Chengdu, China
Peter Grünberg Institute (PGI-8), Research Center Jülich, 52425 Jülich, Germany
Institute of Complex Systems (ICS-6), Research Center Jülich, 52425 Jülich, Germany
Institute of Physical Biology, Heinrich-Heine-University, Düsseldorf, Germany
State Key Laboratory of Functional Materials for Informatics, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 200050 Shanghai, China
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