Tough Antibacterial Metallopolymer Double-Network Hydrogels via Dual Polymerization
Source abstract
Abstract
We report the preparation of tough double-network (DN) metallopolymer antibacterial hydrogels through dual polymerization. DN hydrogels are composed of the first network of cationic cobaltocenium polyelectrolytes enabled using ring-opening metathesis polymerization and the second network of polymers prepared using radical polymerization. These DN hydrogels exhibited a very high compressive stress (up to ∼120 MPa). The introduction of boronic acid and ionic conjugation with β-lactam antibiotics endowed the hydrogels with high antimicrobial efficacy against both Gram-positive and Gram-negative bacteria.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced Polymer Synthesis and Characterization · Antimicrobial agents and applications · Polymer Surface Interaction Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry and Biochemistry, University of South Carolina, Columbia, South Carolina 29208, United States
Funding
National Institute of Allergy and Infectious Diseases · Office of Integrative Activities
References (69)
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