Sensitive and Selective Label-Free DNA Detection by Conjugated Polymer-Based Microarrays and Intercalating Dye
Source abstract
Abstract
We have demonstrated label-free and signal-amplifying DNA microarray using a conjugated polymer and an intercalating dye SYBR green I. Efficient FRET from the conjugated polymer to the dye produced large signal amplification so that without losing good selectivity, sensitive detection of subpicomolar concentrations of the target DNA was achieved.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Advanced Biosensing Techniques and Applications · Biosensors and Analytical Detection
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Departments of Materials Science and Engineering, Chemical Engineering, Macromolecular Science and Engineering, and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109
References (22)
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