journal article·2016-06-14

Hydrophobic Hydrogels: Toward Construction of Floating (Bio)microdevices

Nuno M. Oliveira, Yu Shrike Zhang, Jie Ju, Ai-Zheng Chen, Yu Chen, Sameer R. Sonkusale, Mehmet Remzi Dokmeci, Rui L. Reis, João F. Mano, Ali Khademhosseini

Chemistry of Materials· Volume 28· Issue 11
Publisher page

Abstract

Hydrogels, formed through cross-linking of hydrophilic polymer chains, represent a class of materials that are capable of holding large volumes of water. Here we report a novel class of hydrophobic hydrogels that can free-float on the surface of different aqueous media by coating conventional hydrogels with a layer of hydrophobic microparticles. We further demonstrate that these floating hydrogel-based devices can be used for sensing applications on liquid surfaces such as the construction of floating pH meters. Moreover, we demonstrate that the floating hydrogels present high mobility with excellent self-assembling property on the surface of water. Importantly, the floating systems reserved the intrinsic biocompatibility of the core hydrogels, enabling microengineering of floating tissue constructs. It is expected that these floating hydrophobic hydrogel-based devices will likely find widespread applications including but not limited to sensing, tissue engineering, and biomedicine.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research · Hydrogels: synthesis, properties, applications · Innovative Microfluidic and Catalytic Techniques Innovation

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

3B’s Research Group − Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Zona Industrial da Gandra, 4805-017 Barco GMR, Portugal

ICVS/3B’s − PT Government Associate Laboratory, Braga/Guimarães 4710-057, Portugal

Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts 02115, United States

Institute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian 362021, P.R. China

Nanolab, Department of Electrical Engineering, Tufts University, Medford, Massachusetts 02155, United States

Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea

Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia

Funding

National Heart, Lung, and Blood Institute · National Institute of Dental and Craniofacial Research · National Institute of Allergy and Infectious Diseases · National Institute of Biomedical Imaging and Bioengineering · Office of Naval Research · U.S. Department of Defense · National Institute of Arthritis and Musculoskeletal and Skin Diseases · Fundação para a Ciência e a Tecnologia

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