journal article·2006-02-21

Surface Modification Using Cubic Silsesquioxane Ligands. Facile Synthesis of Water-Soluble Metal Oxide Nanoparticles

Benjamin L. Frankamp, Nicholas O. Fischer, Rui Hong, Sudhanshu Srivastava, Vincent M. Rotello

Chemistry of Materials· Volume 18· Issue 4
Publisher page

Abstract

The use of magnetic nanoparticles in biological applications is hampered by the lack of versatile methods to transfer them into aqueous solutions. Monolayer exchange using anionic octa(tetramethylammonium)−polyhedral oligomeric silsesquioxane provides individual particles that are soluble in aqueous environments and possess excellent stability in biologically relevant pH ranges and salt concentrations. In addition, this surface exchange reaction proved to be general in nature, allowing facile functionalization of a variety of magnetic nanoparticles.
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Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Characterization and Applications of Magnetic Nanoparticles · ZnO doping and properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry and Molecular and Cellular Biology Program, University of MassachusettsAmherst, Amherst, Massachusetts 01003

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