Assembly, Two-Photon Absorption, and Bioimaging of Living Cells of A Cuprous Cluster
Source abstract
Abstract
A novel cuprous(I) cluster Cu 4 I 4 L 4 (L = ( E )-(4-diethylanilino-styryl)pyridine) bearing strong two-photon absorption (TPA) was obtained using a facile assembly method, and the crystal structure has been determined. Quantum chemical calculations using time-dependent density functional theory (TD-DFT) reveals that the combination of the organic ligands with the three-dimensional Cu 4 I 4 core extends the electronic delocalization in the cluster, leading to strong two-photon absorption action. The TPA cross sections (Φσ 2 ) of Cu 4 I 4 L 4 were enhanced with increasing polarity of solvents, which is quite different from the solvent effects on TPA in the literature. Compared to its free ligand, the cluster Cu 4 I 4 L 4 exhibits larger peak TPA cross sections in the near-infrared region, longer fluorescence lifetimes, higher quantum yield and photostability, lower cytotoxicity, and brighter two-photon fluorescent (TPF) bioimaging. These integrated advantages make it desirable to be applied as a two-photon fluorescent probe for labeling the nucleic acids in live cells.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Metal complexes synthesis and properties · Nonlinear Optical Materials Studies · Porphyrin and Phthalocyanine Chemistry
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui University, Hefei, 230039, P. R. China
Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom
Department of Physics, Shandong Normal University; Jinan 250014, P. R. China
State Key Laboratory of Crystal Materials, Shandong University, Jinan, 250100, P. R. China
State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing, 230039, P. R. China
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