journal article·2004-09-01

Modified Polyelectrolyte Microcapsules as Smart Defense Systems

Dmitry G. Shchukin, Tatsiana Shutava, Elena Shchukina, Gleb B. Sukhorukov, Yuri M. Lvov

Chemistry of Materials· Volume 16· Issue 18
Publisher page

Abstract

A new type of protective microcontainer, capable of preventing oxidation of encapsulated compounds by low molecular weight oxidizing agents, was demonstrated. These microcontainers (microcapsules) are hollow spheres with the shell made of layer-by-layer assembled polyelectrolytes with an engineered outermost layer. The protecting ability of the developed polyelectrolyte capsules was monitored by oxidation of encapsulated bovine serum albumin by H 2 O 2 dissolved in aqueous solution. Different catalysts for H 2 O 2 decomposition (catalase, Fe 3 O 4 nanoparticles) were deposited onto the polyelectrolyte shell to increase the protection efficiency. The highest protection activity was observed for poly(allylamine)/poly(styrene sulfonate) capsules containing nano-Fe 3 O 4 in the polyelectrolyte shell.
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Research context

OpenAlex topics: Polymer Surface Interaction Studies · Dendrimers and Hyperbranched Polymers · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute for Micromanufacturing, Louisiana Tech University, Ruston, Louisiana 71272, Institute of Bioorganic Chemistry, Belarusian Academy of Sciences, 220141 Minsk, Belarus, and Max Planck Institute of Colloids and Interfaces, D14424 Potsdam, Germany

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