A Novel and Simple Alcohol-Free Sol−Gel Route for Encapsulation of Labile Proteins
Source abstract
Abstract
This work presents a novel and simple aqueous sol−gel route for the encapsulation of biomolecules, which are labile to the alcohol that results as a byproduct of the matrix formation. The controlled vacuum evaporation of the alcohol by rotavapor methods provides an aqueous sol in which the activity of labile biomolecules is preserved. The versatility of this approach is remarkable since it allows the preparation of pure silica matrixes as well as ormosils.
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Research context
OpenAlex topics: Mesoporous Materials and Catalysis · Analytical Chemistry and Chromatography · Innovative Microfluidic and Catalytic Techniques Innovation
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Affiliations
Instituto de Ciencia de Materiales de Madrid-ICMM, Consejo Superior de Investigaciones Científicas-CSIC, Cantoblanco, 28049 Madrid, Spain, and Instituto Nacional de Tecnología Aeroespacial-INTA, Laboratorio de Instrumentación Espacial-LINES, Torrejón de Ardoz, 28850 Madrid, Spain
References (25)
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