journal article·2007-10-01

The Organic−Mineral Interface in Bone Is Predominantly Polysaccharide

Erica R. Wise, Sergey Maltsev, M. Elisabeth Davies, Melinda J. Duer, Christian Jaeger, Nigel Loveridge, Rachel C. Murray, David G. Reid

Chemistry of Materials· Volume 19· Issue 21
Publisher page

Abstract

By identifying the carbon atoms in close proximity to the mineral suface in bone, solid-state NMR shows that the vital interface between it and the organic matrix is principally polysaccharide and not protein. The discovery has implications for bone health and design of osteomimetic materials.
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Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Bone Metabolism and Diseases · Supramolecular Chemistry and Complexes

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K., Federal Institute of Materials Research and Testing (BAM), Richard Willstaeter Str. 11, D-12489, Germany, Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, U.K., Department of Medicine, Addenbrookes Hospital, Hills Road, Cambridge CB2 2QQ, U.K., and Animal Health Trust, Lanwades Park, Newmarket, Suffolk CB8 7UU, U.K.

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